Cas No.: | 1239262-36-2 |
Chemical Name: | (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride |
Synonyms: | S2101 |
Formula: | C16H15F2NO.HCl |
M.Wt: | 311.75 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | S-2101 is a potent lysine-specific demethylase 1 (LSD1) inhibitor with Ki of 0.61 uM; displays weaker inhibition to MAO-B and MAO-A compared with Tranylcypromine (2-PCPA); protects against cisplatin-induced hair cell loss by preventing demethylation of histone H3K4 (H3K4me2); induces cytotoxicity in ovarian cancer lines. |