Cas No.: | 1207195-45-6 |
Chemical Name: | 1-[1-(2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl)-4-piperidinyl]-1,3-dihydro-2H-indol-2-one |
Synonyms: | SR16835 |
Formula: | C26H30N2O |
M.Wt: | 386.54 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | SR-16835 is a potent full agonist of ORL1 receptor (NOP receptor) with binding Ki of 11.4 nM, with low-affinity mu-opioid partial agonist activity (Ki=79.9 nM); does not produce conditioned place preference (CPP) alone, but attenuates morphine CPP; shows antiallodynic activity in mice model of chronic pain. |