Cas No.: | 677773-91-0 |
Chemical Name: | Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate |
Synonyms: | SM324405 |
SMILES: | COC(=O)CC1C=CC=C(CN2C(=O)NC3C2=NC(OCCCC)=NC=3N)C=1 |
Formula: | C19H23N5O4 |
M.Wt: | 385.424 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | SM-324405 is a potent, selective TLR7 agonist with EC50 of 50 nM, induces IFN-α and -γ expression in human PBMCs and mouse splenocytes, inhibits IL-5 production in human PBMCs in vitro. |