Cas No.: | 864941-32-2 |
Chemical Name: | ethyl (2-(benzo[d]thiazole-2-carboxamido)thiophene-3-carbonyl)carbamate |
Synonyms: | TCA1 |
Formula: | C16H13N3O4S2 |
M.Wt: | 375.417 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A small molecule with activity against drug-resistant and persistent tuberculosis; shows bactericidal activity against nonreplicating Mtb in vitro and is efficacious in acute and chronic Mtb infection mouse models; down-regulates genes known to be involved in Mtb persistence; inhibits DprE1 and MoeW, enzymes involved in cell wall and molybdenum cofactor biosynthesis. |