Cas No.: | 2799-07-7 |
Chemical Name: | S-(Triphenylmethyl)-L-cysteine |
Synonyms: | NSC 83265 |
SMILES: | C(SCC(C(O)=O)N)(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1 |
Formula: | C22H21NO2S |
M.Wt: | 363.47 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM); induces mitotic arrest in HeLa cells with an IC50 of 700 nM, and displays antitumor activity. |