Cas No.: | 1591932-50-1 |
Chemical Name: | N-[4-(2-hydrazinylethyl)phenyl]-benzenebutanamide |
Formula: | C18H23N3O |
M.Wt: | 297.402 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Bizine is a phenelzine analog that inhibits LSD1 with Ki of 59 nM, displays 23-fold, 63-fold, and >100-fold selectivity for LSD-1 over MAOA, MAOB, and LSD2 respectively; induces bulk histone H3 lysine 4 dimethylation in LNCaP cancer cells (EC50=2 uM), and protects neurons exposed to oxidative stress at 0.5 uM. |