Cas No.: | 1092797-77-7 |
Chemical Name: | 4-(2-Chlorophenyl)butan-2-amine hydrochloride |
Formula: | C10H15Cl2N |
M.Wt: | 220.137 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | SK609 (SK-609, ES609) is a potent, selective agonist of dopamine D3 receptor with a bias towards the G-protein-dependent pathway rather than recruiting β-arrestin-2 and an EC50 value of 113.9 nM for activation of ERK1/2 phosphorylation; reverses akinesia and reduces L-dopa-induced dyskinesia in a hemiparkinsonian rat model of Parkinson's desease. |