Cas No.: | 1434873-26-3 |
Chemical Name: | (2-benzhydryl-5-methyl-1H-imidazole-4-carbonyl)-L-arginine |
Synonyms: | BR 103 |
Formula: | C24H28N6O3 |
M.Wt: | 448.527 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats. |