FH1(BRD-K4477)

Cas No.:	2719-05-3
Chemical Name:	4,4'-Diacetamidodiphenylmethane
Synonyms:	Acetamide,N,N'-(methylenedi-4,1-phenylene)bis-;FH1;4,4'-DIACETAMIDODIPHENYLMETHANE;FH1(BRD-K4477);4,4'-diacetoamino-diphenylmethane;4,4'-Diacetyldiaminodiphenylmethan;4',4''-METHYLENEBIS(ACETANILIDE);4.4'-Bis-acetamino-diphenylmethan;BRDK4477;BRD-K4477;N,N'-AcetylMDA;N,N'-diacetyl-4,4'-methylenedianiline;NSC 12407;N,N′-(Methylenedi-4,1-phenylene)bis-acetamide;N,N′-(Methylenedi-4,1-phenylene)diacetamide;N,N'-(Methylenebis(4,1-phenylene))diacetamide;FH 1;Bis(4-acetamidophenyl)methane;Methylenebis-4,4'-acetanilide;N,N'-Diacetyl-4,4'-diaminodiphenylmethane;Acetamide, N,N'-(methylenedi-4,1-phenylene)bis-;N,N'-(4,4'-methylenebis(4,1-phenylene))diacetamide;N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide;N,N'-(methylenedi-4,1-phenylene)bis(acetamide);N-{4-[(4-Acetamidophenyl)methyl]phenyl}acetamide;NSC12407;N,N'-AcetylM
SMILES:	O=C(C([H])([H])[H])N([H])C1C([H])=C([H])C(=C([H])C=1[H])C([H])([H])C1C([H])=C([H])C(=C([H])C=1[H])N([H])C(C([H])([H])[H])=O
Formula:	C17H18N2O2
M.Wt:	282.3370
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	FH1(BRDK4477) is a small molecule that can enhance the functions of cultured hepatocytes.IC50 value:Target: In vitro: FH1(BRD-K4477) enhances hepatocyte functions, and promotes the maturation of well-differentiated cultures of iHeps, which potentially alleviates a major obstacle to the use of iPS cells as a renewable source of functional human hepatocytes.
References:	[1]. Shan J, et al. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat Chem Biol. 2013 Aug;9(8):514-20.