HQL-79

  Cat. No.:  DC7425  
Chemical Structure
162641-16-9
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More than 5000 active chemicals with high quality for research!
Field of application
Orally active and specific inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50 = 6 μM). Antiallergic and anti-inflammatory.
Cas No.: 162641-16-9
Chemical Name: 4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine
Synonyms: HQL 79,HQL79
SMILES: C(C1=CC=CC=C1)(OC2CCN(CCCC3=NN=NN3)CC2)C4=CC=CC=C4
Formula: C22H27N5O
M.Wt: 377.48
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Orally active and specific inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50 = 6 μM). Antiallergic and anti-inflammatory; displays antiasthmatic activity and potent antihistaminic properties in vivo.For the detailed information of HQL-79, the solubility of HQL-79 in water, the solubility of HQL-79 in DMSO, the solubility of HQL-79 in PBS buffer, the animal experiment (test) of HQL-79, the cell expriment (test) of HQL-79, the in vivo, in vitro and clinical trial test of HQL-79, the EC50, IC50,and Affinity of HQL-79, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC42503 Taprenepag isopropyl Taprenepag isopropyl is a highly selective EP2 receptor agonist.
DC47374 Aligeron Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
DC47373 CAY10580 CAY10580 is a potent and selective prostaglandin EP4 receptor agonist (Ki=35 nM).
DC47183 Aganepag isopropyl Aganepag isopropyl (AGN-210961) is an EP2 agonist.
DC47172 15-Keto latanoprost 15-Keto latanoprost is a metabolite of Latanoprost, which is an ocular hypotensive agent.
DC47127 Pexopiprant Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki < 100nM. Pexopiprant can be used in studies of asthma.
DC47089 Treprostinil palmitil Treprostinil palmitil (TP) is the prodrug of DP1 and EP2 agonist, Treprostinil (UT-15), whose EC50 values were 0.6 and 6.2 nM, respectively. Treprostinil palmitil is a pure prodrug and possesses no inherent binding to G-protein coupled receptors including prostanoid receptors.
DC46853 BGC-20-1531 free base BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP4 receptor antagonist, with a pKb of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache.
DC46564 Bimatoprost D5 Bimatoprost D5 (AGN 192024 D5) is a deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog and is a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. Bimatoprost also has an antiadipogenic effect.
DC45799 TCS 2510 TCS 2510 is a selective EP4 agonist. TCS 2510 can be used for the research of metabolic diseases.
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