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| Cas No.: | 1350920-22-7 |
| Chemical Name: | N-Benzyl-N-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide |
| Synonyms: | N-benzyl-N-Methyl-1-(4-(trifluoroMethyl)benzyl)piperidine-3-carboxaMide;N-benzyl-N-methyl-1-{[4-(trifluoromethyl)phenyl]methyl}piperidine-3-carboxamide;N-benzyl-N-methyl-1-[[4-(trifluoromethyl)phenyl]methyl]piperidine-3-carboxamide;BCP13574;AK199784;T.cruzi-IN-1 |
| SMILES: | FC(C1C([H])=C([H])C(=C([H])C=1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])(C(N(C([H])([H])[H])C([H])([H])C2C([H])=C([H])C([H])=C([H])C=2[H])=O)C1([H])[H])(F)F |
| Formula: | C22N2OF3H25 |
| M.Wt: | 390.4419 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease[1]. |
| In Vitro: | T.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 μM for toxicity[1]. |
| References: | [1]. Germain AR, et al. Identification of small-molecule inhibitors of Trypansoma cruzi replication. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7197-200. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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