MIF-1

  Cat. No.:  DC11353  
Chemical Structure
2002-44-0
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More than 5000 active chemicals with high quality for research!
Field of application
Melanocyte-stimulating hormone release-inhibiting factor (MSH-R-IF) is a hypothalamic tripeptide that binds to rat striatum (Kd = 4.69 nM) and has diverse biological activities.
Cas No.: 2002-44-0
Synonyms: MIF-1;MSH-R-IF;Melanocyte-Stimulating Hormone Release-Inhibiting Factor
SMILES: O=C([C@@H](NC([C@H]1NCCC1)=O)CC(C)C)NCC(N)=O
Formula: C13H24N4O3
M.Wt: 284.4
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Melanocyte-stimulating hormone release-inhibiting factor (MSH-R-IF) is a hypothalamic tripeptide that binds to rat striatum (Kd = 4.69 nM) and has diverse biological activities.In vivo, MSH-R-IF (0.1 mg/kg) decreases immobility of mice in the forced swim test, indicating antidepressant-like activity.MSH-R-IF (20 mg/kg) increases striatal concentration of dopamine and the dopamine metabolites DOPAC, 3-methoxy tyramine, and homovanillic acid (HVA) in a mouse model of Parkinson's disease induced by MPTP.It decreases vacuous chewing movements induced by haloperidol in a rat model of tardive dyskinesia when administered at a dose of 2 mg/kg.4 MSH-R-IF also has anti-opiate effects, reversing analgesia induced by morphine and an enkephalin in mice in a radiant heat tail-flick assay.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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