Meleagrin|cas 71751-77-4|DC Chmeicals

Cas No.:	71751-77-4
SMILES:	N1C=C(NC=1)\C=C2/N3C4(NC2=O)C(C(C)(C)C=C)(C=C(O)C3=O)C5C(=CC=CC=5)N4OC
Formula:	C₂₃H₂₃N₅O₄
M.Wt:	433.5
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Meleagrin is an antibiotic derived from a deep ocean, penicillin-producingP. chrysogenum.It is produced as an end product in the roquefortine branched biosynthetic pathway.Meleagrin has been identified as an inhibitor of the bacterial enoyl-acyl carrier protein reductase (FabI) with IC50 values of 40.1 and 33.2 µM for S. aureus and E. coli FabI, respectively.1 It inhibits the growth of S. aureus, E. coli, and S. pneumoniae with MICs ranging from 32-64 µg/ml. For the detailed information of Meleagrin, the solubility of Meleagrin in water, the solubility of Meleagrin in DMSO, the solubility of Meleagrin in PBS buffer, the animal experiment (test) of Meleagrin, the cell expriment (test) of Meleagrin, the in vivo, in vitro and clinical trial test of Meleagrin, the EC50, IC50,and affinity,of Meleagrin, For the detailed information of Meleagrin, the solubility of Meleagrin in water, the solubility of Meleagrin in DMSO, the solubility of Meleagrin in PBS buffer, the animal experiment (test) of Meleagrin, the cell expriment (test) of Meleagrin, the in vivo, in vitro and clinical trial test of Meleagrin, the EC50, IC50,and affinity,of Meleagrin, Please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC47250	Nonanal	Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity.
DC47249	Piperitone	Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity.
DC47247	Tyrosylleucine TFA	Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47243	Dehydroglyasperin C	Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities.
DC47227	(−)-Myrtenal	(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
DC47224	GPX4-IN-3	GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.
DC47179	Tyrosylleucine	Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47178	Mead acid	Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency.
DC47140	Yadanzioside K	Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
DC47105	Complanatoside B	Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.