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Pipequaline

  Cat. No.:  DC10113   Featured
Chemical Structure
77472-98-1
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More than 5000 active chemicals with high quality for research!
Field of application
Pipequaline (PK 8165) is a partial benzodiazepine receptor agonist with anxiolytic activity.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 77472-98-1
Chemical Name: PK-8165; PK8165; PK 8165
Synonyms: PK-8165; PK8165; PK 8165
SMILES: C1CNCCC1CCC2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4
Formula: C22H24N2
M.Wt: 316.44
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Pipequaline (PK 8165) is a non-selective GABAA receptor partial agonist with anxiolytic activity.
In Vivo: Intravenously administered pipequaline exerts a partial suppression of activations by kainate, glutamate and acetylcholine. Microiontophoretic applications of pipequaline reduces the neuronal activation by kainate[2]. Pipequaline produces dose-related decreases in motor activity. Pipequaline produces significant dose-related decreases in the number of head-dips made[3].
In Vitro: Pipequaline is extensively bound to plasma proteins: i.e. human serum albumin (HSA), alpha-1-acid glycoprotein (AAG), lipoproteins and blood cells, mainly erythrocytes[1].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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