SKF-82958 (hydrobromide)|cas 74115-01-8|DC Chemicals

Cas No.:	74115-01-8
Synonyms:	(±)-SKF 82958 hydrobromide;Chloro-APB hydrobromide
SMILES:	OC1=C(O)C=C2C(C3=CC=CC=C3)CN(CC=C)CCC2=C1Cl.[H]Br
Formula:	C₁₉H₂₁BrClNO₂
M.Wt:	410.7325
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

SKF 82958 hydrobromide is a D1/D5 receptor full agonist. in vitro: Neuropeptide and immediate early gene expression in striatonigral neurons of the normosensitive striatum is induced by mixed D1 receptor SKF-82958, which induces behavioral activity and preprodynorphin (PPD) and substance P (SP) gene expression in medium spiny neurons in the dorsal, and especially, in the ventral striatum. in vivo:Quantitative in situ hybridization was used to examine the contribution of muscarinic receptors to the transynaptic regulation of striatal gene expression induced by D1receptor activation. The acute injection of the full D1 agonist, SKF-82958, would induce PPD, SP and PPE mRNA expression in the intact rat striatum.

MSDS

COA

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2018-0101

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