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SM-04554

  Cat. No.:  DC33839   Featured
Chemical Structure
1360540-81-3
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More than 5000 active chemicals with high quality for research!
Field of application
SM04554 is a topical Wnt pathway activator for the treatment of androgenetic alopecia (AGA).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1360540-81-3
Chemical Name: 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4-phenylbutane-1,4-dione
Synonyms: SM-04554; SM 04554; SM04554
SMILES: O=C(C1=CC=C2OCCOC2=C1)CCC(C3=CC=CC=C3)=O
Formula: C18H16O4
M.Wt: 296.32
Purity: >98%
Sotrage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Description: SM-04554 is a potent Wnt activator extracted from patent WO2012024404A1, compound 1, has an IC50s of 28-29 nM[1].
Target: IC50: 28-29 nM (Wnt)[1]
References: [1]. Charlene F. Barroga, et al. Diketones and hydroxyketones as catenin signaling pathway activators. WO2012024404A1.
MSDS
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MSDS_16150_DC33839
COA
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Cat. No. Product name Field of application
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DC74555 GYS32661 GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays.
DC74539 L557-0155 L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.
DC74528 K284 K284 is a selective small molecule inhibitor of chitinase 3 like1 (CHI3L1) with strong binding affinity (Kd=-9.7 kcal·mol-1), inhibits lung metastasis by blocking IL-13Rα2-mediated JNK-AP-1 signals.
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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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