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Sitamaquine tosylate

  Cat. No.:  DC41128  
Chemical Structure
1019640-33-5
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Field of application
Sitamaquine (WR 6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1019640-33-5
Chemical Name: Sitamaquine tosylate
SMILES: CC1=CC=NC2=C(NCCCCCCN(CC)CC)C=C(OC)C=C12.O=S(C3=CC=C(C)C=C3)(O)=O
Formula: C28H41N3O4S
M.Wt: 515.71
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC47406 Antileishmanial agent-2 Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells.
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DC47403 TCMDC-136230 TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
DC47402 TCMDC-125457 TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
DC47401 Antileishmanial agent-1 Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM).
DC47400 BRD5018 BRD5018 is an antimalarial agent.
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DC47107 14-Deoxy-11-oxoandrographolide 14-Deoxy-11-oxoandrographolide is an antileishmanial agent. 14-Deoxy-11-oxoandrographolide inhibits the replication of heal chikungunya virus (CHIKV) and can be used for CHIKV infection research.
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