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Sumanirole maleate

  Cat. No.:  DC10349   Featured
Chemical Structure
179386-44-8
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More than 5000 active chemicals with high quality for research!
Field of application
Sumanirole maleate(PNU 95666E; U95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 179386-44-8
Chemical Name: (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate
Synonyms: (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Z)-2-butenedioate;Sumanirole maleate;U 95666E(SUMANIROLE MALEATE);, Sumanirole maleate, PNU 95666, U95666E;cc-479;PNU 95666;S2191_Selleck;SureCN1229224;U 95666E, Sumanirole maleate, PNU 95666, U95666E;UNII-2OI87T3R1B;(5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate;(R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate;CID 9818479 maleate;PNU-95,666 maleate;U95666E;PNU 95666E
SMILES: OC(=O)\C=C\C(O)=O.CNC1CN2C3C(=CC=CC=3C1)NC2=O
Formula: C11H13N3O.C4H4O4
M.Wt: 319.31258
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Sumanirole maleate(PNU 95666E; U95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM.Sumanirole was developed for the treatment of Parkinson's disease and restless leg syndrome. While it has never been approved for medical use. Sumanirole is a highly valuable tool compound for basic research to identify neurobiological mechanisms that are based on a dopamine D2-linked (vs. D1, D3, D4, and D5-linked) mechanism of action.
Target: D2 receptor
References: [1]. Arthur G. Romero, et al. Synthesis of the Selective D2 Receptor Agonist PNU-95666E fromD-Phenylalanine Using a Sequential Oxidative CyclizationStrategy. J. Org. Chem. 1997, 62, 6582-6587
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
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