URB754(URB-754)|MAGL inhibitor|DC Chemicals

Cas No.:	86672-58-4
Chemical Name:	6-methyl-2-[(4-methylphenyl)amino]-1-benzoxazin-4-one
Synonyms:	URB754,URB 754,URB-754
SMILES:	CC1=CC=C(C=C1)NC2=NC3=C(C=C(C=C3)C)C(=O)O2
Formula:	C₁₆H₁₄N₂O₂
M.Wt:	266.29
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

URB-754 is a new class of designer drug and 12 synthetic cannabinoids detected in illegal products.URB-754 was reported to inhibit an endocannabinoid deactivating enzyme.Subsequent studies have shown that that URB-754 does not inhibit recombinant MAG Lipase and that the original activity was due to a contaminant, bis(methylthio)mercurane, in another commercial source. URB-754 is an inhibitor of FAAH. For the detailed information of URB754, the solubility of URB754 in water, the solubility of URB754 in DMSO, the solubility of URB754 in PBS buffer, the animal experiment (test) of URB754, the cell expriment (test) of URB754, the in vivo, in vitro and clinical trial test of URB754, the EC50, IC50,and affinity,of URB754, For the detailed information of URB754, the solubility of URB754 in water, the solubility of URB754 in DMSO, the solubility of URB754 in PBS buffer, the animal experiment (test) of URB754, the cell expriment (test) of URB754, the in vivo, in vitro and clinical trial test of URB754, the EC50, IC50,and affinity,of URB754, Please contact DC Chemicals.

MSDS

COA

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2018-0101

Cat. No.	Product name	Field of application
DC47250	Nonanal	Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity.
DC47249	Piperitone	Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity.
DC47247	Tyrosylleucine TFA	Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47243	Dehydroglyasperin C	Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities.
DC47227	(−)-Myrtenal	(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
DC47224	GPX4-IN-3	GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.
DC47179	Tyrosylleucine	Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47178	Mead acid	Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency.
DC47140	Yadanzioside K	Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
DC47105	Complanatoside B	Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.