Cixutumumab
Cat. No.: A210
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Chemical Structure
947687-12-9
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Field of application
Cixutumumab (IMC-A12) is a human anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer.
Cas No.: |
947687-12-9 |
pH value: |
Corresponds to reference standard: PASS |
Non-reduced CE-SDS: |
>95% |
SEC-HPLC: |
>95% |
Isoelectric Point: |
Corresponds to reference standard |
Osmolality: |
Corresponds to reference standard: PASS |
Peptide mapping: |
Corresponds to reference standard: PASS |
N-terminal sequence: |
Corresponds to reference standard: PASS |
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