Empasiprubart

  Cat. No.:  A829   Featured
Chemical Structure
2579031-19-7
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More than 5000 active chemicals with high quality for research!
Field of application
Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models.
Cas No.: 2579031-19-7
pH value: Corresponds to reference standard: PASS
Non-reduced CE-SDS: >95%
SEC-HPLC: >95%
Isoelectric Point: Corresponds to reference standard
Osmolality: Corresponds to reference standard: PASS
Peptide mapping: Corresponds to reference standard: PASS
N-terminal sequence: Corresponds to reference standard: PASS
MSDS
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