Isatuximab
Cat. No.: A768
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Chemical Structure
1461640-62-9
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Field of application
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38, a protein highly expressed on hematological malignant cells, including those in multiple myeloma (MM). Isatuximab has antitumor activity via multiple biological mechanisms, including antibody-dependent cellular-mediated cytotoxicity, complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, and direct induction of apoptosis without crosslinking. Isatuximab also directly inhibits CD38 ectoenzyme activity, which is implicated in many cellular functions.
| Cas No.: |
1461640-62-9 |
| pH value: |
Corresponds to reference standard: PASS |
| Non-reduced CE-SDS: |
>95% |
| SEC-HPLC: |
>95% |
| Isoelectric Point: |
Corresponds to reference standard |
| Osmolality: |
Corresponds to reference standard: PASS |
| Peptide mapping: |
Corresponds to reference standard: PASS |
| N-terminal sequence: |
Corresponds to reference standard: PASS |
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