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CFT7455

  Cat. No.:  DC50245   Featured
Chemical Structure
2504235-67-8
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More than 5000 active chemicals with high quality for research!
Field of application
CFT7455 is an orally bioavailable degrader of the zinc finger transcription factors Ikaros (IKZF1) and Aiolos (IKZF3). It functions as an anticancer agent by binding with high affinity to the cereblon E3 ligase, exhibiting a Kd of 0.9 nM (WO2022032132A1; Compound 1).
Cas No.: 2504235-67-8
Chemical Name: Cemsidomide
Synonyms: 2,​6-​Piperidinedione, 3-​[6-​[[4-​(4-​morpholinylmethyl)​phenyl]​methyl]​-​2-​oxobenz[cd]​indol-​1(2H)​-​yl]​-​, (3S)​-;Cemsidomide
SMILES: O=C1[C@@H](N2C(=O)C3=C4C(C(CC5=CC=C(C=C5)CN5CCOCC5)=CC=C24)=CC=C3)CCC(=O)N1
Formula: C28H27N3O4
M.Wt: 469.53
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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