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Tricin

  Cat. No.:  DC43571   Featured
Chemical Structure
520-32-1
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More than 5000 active chemicals with high quality for research!
Field of application
Tricin is a natural flavonoid present in large amounts in rice bran. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[1][2][3].
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 520-32-1
Chemical Name: Tricin
Synonyms: 5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-5,6-dihydro-4H-chromen-4-one;Tricetin 3',5'-dimethyl ether;5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromen-4-one;5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-chromen-4-one;Tricin;3',5'-DIMETHOXY-4',5,7-TRIHYDROXYFLAVONE;3',5'-O-dimethyltricetin;4',5,7-trihydroxy-3',5'-dimethoxyflavone;5,7,4'-trihydroxy-3',5'-dimethoxyflavone;Tricetin 3',5'-di-methyl ether;tricetine-3',5'-dimethyl ether;4′,5,7-Trihydroxy 3′,5′-dimethoxyflavone;[ "" ];D51JZL38TQ;5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxy-phenyl)chromen-4-one;5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one;3',5'-di-O-methyltricetin;3\\',5\\'-di-O-methyl
SMILES: O1C2=C([H])C(=C([H])C(=C2C(C([H])=C1C1C([H])=C(C(=C(C=1[H])OC([H])([H])[H])O[H])OC([H])([H])[H])=O)O[H])O[H]
Formula: C17H14O7
M.Wt: 330.2889
Purity: >98%
Sotrage: 0°C (short term), -20°C (long term), desiccated
Publication: [1]. Itoh A, et al. Tricin inhibits the CCL5 induction required for efficient growth of human cytomegalovirus. Microbiol Immunol. 2018 May;62(5):341-347. [2]. Sadanari H, et al. The anti-human cytomegalovirus drug tricin inhibits cyclin-dependent kinase 9. FEBS Open Bio. 2018 Feb 20;8(4):646-654. [3]. Chung DJ, et al. Inhibition of the Proliferation and Invasion of C6 Glioma Cells by Tricin via the Upregulation of Focal-Adhesion-Kinase-Targeting MicroRNA-7. J Agric Food Chem. 2018 Jul 5;66(26):6708-6716.
MSDS
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MSDS_27192_DC43571_520-32-1
COA
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Cat. No. Product name Field of application
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DC31074 Isopropyl myristate Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC74583 ZK53 ZK53 is a selective activator of mitochondrial caseinolytic protease P (HsClpP). It exhibits an EC50 of 1.37 μM for α-casein hydrolysis by HsClpP. ZK53 treatment allosterically activates HsClpP to uncontrollably degrade the essential mitochondrial proteins and is inactive toward bacterial ClpP proteins.
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DC74555 GYS32661 GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays.
DC74539 L557-0155 L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.
DC74528 K284 K284 is a selective small molecule inhibitor of chitinase 3 like1 (CHI3L1) with strong binding affinity (Kd=-9.7 kcal·mol-1), inhibits lung metastasis by blocking IL-13Rα2-mediated JNK-AP-1 signals.
DC74247 AG-946 AG-946 (AG946) is a potent, allosteric activator of wild-type and mutant RBC-specific form of pyruvate kinase (PKR) with AC50 of 5 nM for human wild-type PK, 4.3 nM and 6.9 nM for mutated K410E and R510Q PK proteins, resepctively.
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