Cat. No. | Product name | CAS No. |
DC73226 |
Netarsudil
Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2. |
1254032-66-0 |
DC73227 |
DIZ-3
DIZ-3 is a dimeric aryl-substituted imidazole as a selective multimeric G-quadruplex (G4) ligand, intercalates into the G4-G4 interface, induces cell cycle arrest and apoptosis, and inhibits cell proliferation in alternative lengthening of telomere (ALT) |
2675490-72-7 |
DC73228 |
Teloxantron
Teloxantron (Telomerase inhibitor TXT4) is a potent small molecule inhibitor of telomerase activity with IC50 of 9.61 uM, 7-fold lower than BIBR1532 (Cat# PC-45170), inhibits the processivity of telomerase with preferential DNA damage on telomeres. |
2016813-83-3 |
DC73229 |
LMP744
LMP744 (MJ-III-65, NSC706744) is a small molecule TOP1 inhibitor antitumoral activity. |
308246-52-8 |
DC73217 |
Thioparib
Thioparib is a next-generation potent, orally bioavailable pan-PARP inhibitor with IC50 of 0.13/0.006 nM (PARP1/2), overcomes multiple PARPi resistance both in vitro and in vivo. |
2098639-49-5 |
DC74584 |
LY2880070
LY2880070 is an orally active inhibitor of CHK1. LY2880070 can be used as an anticancer agent and shows promise in preclinical models of pancreatic ductal adenocarcinoma (PDAC) when used in combination with DNA-damaging agents. |
1375637-35-6 |
DC74624 |
Tibremciclib
Tibremciclib is a CDK4 inhibitor with antineoplastic activity. |
2397678-18-9 |
DC74625 |
Votoplam
Votoplam is a gene splicing modulator, used to inhibit Huntington's disease. |
2407849-89-0 |