Cas No.: | 2365193-22-0 |
Chemical Name: | Zelasudil |
SMILES: | O=C(C1=CC=C(C2=NN(C)C(NC3=CC=C4NN=CC4=C3C5CC5)=N2)C=C1)NCC(F)F |
Formula: | C22H21F2N7O |
M.Wt: | 437.45 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Publication: | [1]. Lee E, et al. Selective ROCK2 inhibition for treatment of edema and associated conditions: World Intellectual Property Organization, WO2022169946. 2022-08-11. [2]. WHO Drug Information-World Health Organization (WHO). |
Description: | Zelasudil is a Rho-associated (ROCK) kinase inhibitor. Zelasudil has a ROCK2 binding affinity. |
References: | [1]. Lee E, et al. Selective ROCK2 inhibition for treatment of edema and associated conditions: World Intellectual Property Organization, WO2022169946. 2022-08-11. [2]. WHO Drug Information-World Health Organization (WHO). |