Diethyl Pyrocarbonate

  Cat. No.:  DC72861  
Chemical Structure
1609-47-8
For research use only. We do not sell to patients.
We match the best price and quality on market.
Email:order@dcchemicals.com  sales@dcchemicals.com
Tel:+86-021-58447131
We are official vendor of:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
More than 5000 active chemicals with high quality for research!
Field of application
Diethyl pyrocarbonate is a potent, non-specific inhibitor of RNase. It has been useful as an in vitro agent, relatively specific for binding to imidazole of histidine. It inhibits central chemosensitivity in rabbit and can modify Ser, Thr, His and Tyr residues.
Cas No.: 1609-47-8
Chemical Name: Diethyl pyrocarbonate
Synonyms: Diethyl pyrocarbonate;Diethyl oxydiformate;Ethoxyformic anhydride;Pyrocarbonic acid diethyl ester;Diethyl dicarbonate;dicarbonicaciddiethylester;Diethyl ester of pyrocarbonic acid;Diethyl pyrocarbonic acid;Diethylester kyseliny diuhlicite;DEPC;DIETHYLPYROCARBONATE (DEPC);DEP,DEPC,Diethyl dicarbonate;ethoxycarbonyl ethyl carbonate;Ethoxyformic acid anhydride;DEP;Baycovin;Ethyl pyrocarbonate;Diethylpyrocarbonate;Dicarbonic acid, diethyl ester;Dicarbonic acid diethyl ester;Piref;Diethylpyrokarbonat;Oxydiformic acid diethyl ester;Pyrocarbonate d'ethyle;Pyrokohlensaeure diaethyl ester;Pyrocarbonic acid, diethyl ester
SMILES: O(C(=O)OC(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
Formula: C6H10O5
M.Wt: 162.1406
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Diethyl pyrocarbonate is a potent, non-specific inhibitor of RNase. It has been useful as an in vitro agent, relatively specific for binding to imidazole of histidine. It inhibits central chemosensitivity in rabbit and can modify Ser, Thr, His and Tyr residues.
References: [1]. E E Nattie. Diethyl pyrocarbonate (an imidazole binding substance) inhibits rostral VLM CO2 sensitivity. J Appl Physiol (1985). 1986 Sep;61(3):843-50.
MSDS
Cat. No. Product name Field of application
DC72861 Diethyl Pyrocarbonate Diethyl pyrocarbonate is a potent, non-specific inhibitor of RNase. It has been useful as an in vitro agent, relatively specific for binding to imidazole of histidine. It inhibits central chemosensitivity in rabbit and can modify Ser, Thr, His and Tyr residues.
DC72313 Dideoxy-amanitin Dideoxy-amanitin (compound 2), an α-Amanitin derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC50 value of 74.2 nM.
DC72169 RP-6685 RP-6685 is a potent, selective and orally active DNA polymerase theta (Polθ) inhibitor with an IC50 value of 5.8 nM (PicoGreen assay). RP-6685 shows antitumor efficacy in mouse tumor xenograft model.
DC71300 Branaplam hydrochloride Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model.
DC45554 Aplidine Aplidine (Plitidepsin) is a potent anti-cancer agent by targeting eEF1A2 ( KD=80 nM). Aplidine possesses antiviral activity and is against SARS-CoV-2 with an IC90 of 0.88 nM. Aplidine is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research.
DC44851 CHAPS CHAPS is a zwitterionic surfactant that decreases the sequence specificity of the nucleosome.,nucleosome [1]()
DC44137 5-Propargylamino-ddUTP 5-Propargylamino-ddUTP, a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis.
DC42487 Datelliptium chloride hydrochloride Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from Ellipticine. Datelliptium chloride hydrochloride is effective in vivo against a variety of murine solid tumors.
DC42292 DENV-IN-2 DENV-IN-2 is a potent dengue viral replication extracted from patent WO2018215315A1, compound 6AB, has an EC50 of 0.016 nM. DENV-IN-2 shows high potent activity against all four serotypes of the Dengue virus with EC50s ranging from 0.013 to 0.029 nM.
DC40993 Remdesivir O-desphosphate acetonide impurity Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro.
X