Cat. No. | Product name | CAS No. |
DC5133 |
SNX-2112 (PF-04928473)
Featured
SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, uniformly more potent than 17-AAG. |
908112-43-6 |
DC7287 |
Ralfinamide
Featured
Sodium channel blocker. Suppresses tetrodotoxin (TTX)-resistant Na+ currents approximately twice as selectively as TTX-sensitive currents. Antinociceptive; displays analgesic effects in animal models of inflammatory and neuropathic pain. |
202825-45-4 |
DC8384 |
Sodium Tauroursodeoxycholate (TUDC)
Featured
Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis. |
35807-85-3 |
DC8169 |
Solcitinib(GLPG0778)
Featured
Solcitinib, also known as GSK2586184 or GLPG0778, is a Janus kinase 1 (JAK1) inhibitor. |
1206163-45-2 |
DC9502 |
Solifenacin (hydrochloride)
Featured
Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist. |
180468-39-7 |
DC8800 |
Solifenacin Succinate
Featured
Solifenacin Succinate(YM905; Vesicare) is a muscarinic receptor antagonist. |
242478-38-2 |
DC8032 |
Solithromycin
Featured
Solithromycin is a novel ketolide antibiotic. |
760981-83-7 |
DC11529 |
Solriamfetol hydrochloride
Featured
Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
178429-62-4 |
DC2098 |
Sorafenib (BAY-43-9006)
Featured
Sorafenib Tosylate (Bay 43-9006, Nexavar) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. |
475207-59-1 |
DC8791 |
Sorafenib free base (BAY-43-9006)
Featured
Sorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro. |
284461-73-0 |
DC11101 |
Soticlestat
Featured
Soticlestat is a potent, selective cholesterol 24-hydroxylase inhibitor. |
1429505-03-2 |
DC7506 |
Sotrastaurin
Featured
Sotrastaurin(AEB-071) is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM; inactive to PKCζ. |
425637-18-9 |
DC8599 |
SP 141
Featured
SP 141 is a cell-permeable inhibitor of Mdm2 (Ki = 28 nM). |
1253491-42-7 |
DC7956 |
SP2509
Featured
SP2509 is a novel histone demethylase LSD1 (KDM1A) antagonist with IC50 of 13 nM; no inhibition on MAO-A and MAO-B. |
1423715-09-6 |
DC8039 |
SP-420
Featured
SP-420 is an orally active small molecule that selectively binds iron and removes it from the body. SP-420 has shown excellent tissue penetration, highly efficient iron binding and a promising safety profile. |
911714-45-9 |
DC2095 |
SP600125
Featured
SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM, respectively. |
129-56-6 |
DC26007 |
Spastazoline
Featured
Spastazoline is a potent and selective spastin (a microtubule-severing AAA protein) inhibitor, with an IC50 of 99 nM for Human spastin. Spastazoline shows no effect on ATPase activity of a recombinant human VPS4. |
2351882-11-4 |
DC8319 |
Spautin 1
Featured
Spautin 1 is an inhibitor of autophagy; inhibits USP10 and USP13 activity (IC50 values are 0.6 and 0.7 μM respectively) and promotes degradation of Vps34 (class III PI 3-kinase) complexes. |
1262888-28-7 |
DC20139 |
SPD304
Featured
SPD304 is a selective inhibitor of tumor necrosis factor α (TNFα) and promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor, with an IC50 of 22 µM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α. |
869998-49-2 |
DC24125 |
SPDB
Featured
SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).. |
115088-06-7 |
DC10587 |
SPI 112
Featured
SPI 112 is novel Shp2 PTP inhibitor. |
1051387-90-6 |
DC10690 |
SPI-112Me
Featured
SPI-112Me is a prodrug for SPI-112, which preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by a factor of 20 in cell-free assays. |
1243685-62-2 |