| DC60346 |
UDP 5'-diphospho-a-L-rhamnose
Featured
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| DC60348 |
UDP-6-azido-6-deoxy-D-Gal.2Na
Featured
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| DC60349 |
UDP-b-L-arabinopyranose
Featured
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| DC60350 |
b-Neuraminic acid,N-(hydroxyacetyl)-, 2-(hydrogen 5'-cytidylate) (9CI)
Featured
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| DC60358 |
EDOPC
Featured
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| DC60359 |
Dicetylamine
Featured
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Dicetylamine is a biochemical |
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| DC60362 |
DLenDMA
Featured
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DlenDMA is a lipid for RNA and vaccine delivery. DLenDMA showed better siRNA transfection efficiency than DODMA. |
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| DC60363 |
DOSPER
Featured
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| DC60367 |
EDLPC
Featured
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| DC60368 |
DORIE
Featured
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| DC60378 |
Y-DLenDMA
Featured
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| DC60379 |
HisChol
Featured
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| DC60382 |
Dimyristyloxypropyla mine
Featured
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| DC60385 |
DLin-S-DMA
Featured
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| DC83230 |
TNT-b10
Featured
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TNT-b10 is a novel Lipid-like compound suitable for delivery of siRNA and mRNA both in vitro and in vivo TNT-b10 LLNs was more than 10-fold more potent than TNT-a10 LLNs formulated under the same condition. |
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| DC72591 |
OUL232
Featured
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OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. OUL232 is the most potent PARP10 inhibitor described to date (IC50=7.8 nM), as well as the first PARP12 inhibitor ever reported. |
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| DC72592 |
Zelasudil
Featured
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Zelasudil is a Rho-associated coiled-coil kinase (ROCK) inhibitor with a specific binding affinity for ROCK2, a key enzyme in the Rho/ROCK signaling pathway. This pathway plays a critical role in regulating cellular processes such as cytoskeletal organization, cell motility, smooth muscle contraction, and gene expression. By selectively inhibiting ROCK2, Zelasudil modulates these processes, offering therapeutic potential for a variety of diseases characterized by fibrosis, inflammation, and vascular dysfunction, including pulmonary fibrosis, glaucoma, and cardiovascular diseases. |
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| DC72598 |
EG-011
Featured
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EG-011 is the first-in-class and potent Wiskott-Aldrich syndrome protein (WASP) activator. EG-011 activates the auto-inhibited form of WASP with strong actin polymerization. EG-011 has selective anti-tumor activity in lymphomas. |
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| DC72617 |
LAS190792
Featured
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LAS190792 (AZD8999) is a potent muscarinic antagonist and β2-adrenoceptor agonist with pIC50 8.9, 8.8, 8.8, 9.2, 8.2, 7.5, 9.1, 5.6 for M1, M2, M3, M4, M5, β1, β2, β3, respectively. LAS190792 can be used as a bronchodilator. |
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| DC72629 |
Eucatropine
Featured
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Eucatropine is a synthetic anticholinergic agent that acts as a potent inhibitor of muscarinic acetylcholine receptors (mAChRs). These receptors are part of the parasympathetic nervous system and play a key role in mediating the effects of acetylcholine, a neurotransmitter involved in various physiological processes such as smooth muscle contraction, glandular secretion, and heart rate regulation. |
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| DC72649 |
Nimucitinib
Featured
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Nimucitinib is a Janus kinase (JAK) inhibitor. |
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| DC72651 |
SG-094
Featured
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SG094 is a potent TPC2 inhibitor with antiproliferative effects. SG-094 can be used for the research of cancer. |
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| DC72663 |
SW222746
Featured
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SW222746 (SW 222746) is a potent selective, orally active inhibitor of 15-Prostaglandin dehydrogenase (15-PGDH) with IC50 of 3 nM. |
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| DC72666 |
BMS-820132
Featured
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BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM. |
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| DC72686 |
SP 600125, negative control
Featured
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SP 600125, negative control (SPM1) is an alkyl derivative of pyrazoloanthrone, which can be used as a negative control for SP600125. |
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| DC72699 |
Compound C108
Featured
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Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis. |
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| DC72718 |
S19-1035
Featured
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S19-1035 is a highly potent and specific aldo-keto reductase 1C3 (AKR1C3) inhibitor. S19-1035 inhibits AKR1C3 with an IC50 value of 3.04 nM. S19-1035 can be used for the research of tumor. |
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| DC72724 |
PTC258
Featured
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PTC258 is a specific and orally active splicing modulator of Elongator complex protein 1 gene (ELP1). PTC258 increases the expression of ELP1 in vitro and in vivo. PTC258 is well tolerated in mouse model. |
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| DC72726 |
HQ005
Featured
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HQ005 is a potent CCNK degrader with an DC50 value of 0.041 µM. HQ005 is a molecular-glue degrader that mediates interactions between target proteins and components of the ubiquitin-proteasome system to cause selective protein degradation. |
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| DC72738 |
YLF-466D
Featured
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YLF-466D is an AMPK activator that inhibits platelet aggregation with IC50 of 84 μM. |
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