Cat. No. | Product name | CAS No. |
DC39810 |
ICCB-19
Featured
ICCB-19 inhibits RIPK1-dependent apoptosis (RDA) with IC50 of 2.01 μM. |
750621-52-4 |
DC39811 |
15-Lipoxygenase Inhibitor 1(4-MMPB)
Featured
5-Lipoxygenases (15-LO) inhibitor 1 is a heterocyclic pyrimidobenzothiazine compound that inhibits 15-LO with an IC50 value of 18 µM. |
928853-86-5 |
DC39812 |
CBS-1117
Featured
CBS-1117 is a novel fusion inhibitor with EC50 ∼3 μM against group 1 HA. |
959245-08-0 |
DC39816 |
LDC195943(IMT1)
Featured
LDC195943(IMT1) is a highly specific inhibitor of human mitochondrial RNA polymerase (POLRMT). |
2304621-31-4 |
DC39817 |
LDC203974(IMT1B)
Featured
LDC203974(IMT1B) is a highly specific inhibitor of human mitochondrial RNA polymerase (POLRMT) with improved pharmacokinetic profiles than LDC195943(IMT1). |
2304621-06-3 |
DC39818 |
CL2-SN-38(DCA)
Featured
CL2-SN-38 is a cleavable linker-based antibody-drug conjugate (ADC) containing the topoisomerase I inhibitor SN-38 and a maleimidocaproyl linker. CL2-SN-38 has been linked to tumor-selective human monoclonal antibodies, such as anti-CEACAM5 (hMN-14) to target SN-38 to tumor sites and improve its solubility. CL2-SN-38 linked to hMN-14 binds (Kd = 1.4 nM) and is cytotoxic to LoVo human colon adenocarcinoma cells (IC50 = 5.3 nM). CL2-SN-38 linked to hMN-14 increases survival in a colon carcinoma mouse model of lung metastasis. |
1036969-20-6 |
DC39820 |
DGY-06-116
Featured
DGY-06-116 is an irreversible covalent, selective Src inhibitor. |
2556836-50-9 |
DC39821 |
Finasteride Carboxaldehyde
Featured
Finasteride Carboxaldehyde is a metabolite of Finasteride in human bile (M2 metabolite). |
154387-61-8 |
DC39822 |
GR-125743
Featured
GR 125,743 is a novel 5-HT1B/1D receptor antagonist. |
148547-33-5 |
DC39823 |
Diphenylterazine (DTZ)
Featured
Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios. |
344940-63-2 |
DC39825 |
JC-1
Featured
JC-1 is a membrane-permeable cationic dye that is used to study mitochondrial integrity in the context of cellular apoptosis. |
3520-43-2 |
DC39826 |
Homo-PROTAC cereblon degrader 1
Featured
Homo-PROTAC cereblon degrader 1, is a cereblon degrader. |
2244520-98-5 |
DC39235 |
Fmoc-Val-Ala-PAB-OH
Featured
Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
1394238-91-5 |
DC39827 |
Entecavir Enantiomer
Featured
Enantiomer of Entecavir |
188399-46-4 |
DC42267 |
Eleutheroside D
Featured
Eleutheroside D is an active lignan isolated from the root of Eleutherococcus senticosus, has anti-inflammatory and hypoglycemic activities. Eleutheroside D is an optical isomer of Eleutheroside E. |
79484-75-6 |
DC42268 |
Reuterin
Featured
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates. |
2134-29-4 |
DC42284 |
APG-1387
Featured
APG-1387, a bivalent SMAC mimetic, is an IAP antagonist that can induce proteasomal degradation of IAPs. APG-1387 sensitizes immune-mediated cell apoptosis in cancers. APG-1387 can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma. |
1570231-89-8 |
DC42292 |
DENV-IN-2
Featured
DENV-IN-2 is a potent dengue viral replication extracted from patent WO2018215315A1, compound 6AB, has an EC50 of 0.016 nM. DENV-IN-2 shows high potent activity against all four serotypes of the Dengue virus with EC50s ranging from 0.013 to 0.029 nM. |
2253675-62-4 |
DC42297 |
Vc-MMAD
Featured
Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin (MMAD). Vc-MMAD is a drug-linker conjugate for ADC. |
1401963-17-4 |
DC42300 |
GSK620
Featured
GSK620 is a potent and orally active pan-BD2 with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 |
2088410-46-0 |
DC42314 |
EST73502
Featured
EST73502 is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 has antinociceptive activity. |
1838622-25-5 |
DC42317 |
EST64454 hydrochloride
Featured
EST64454 hydrochloride is a selective and orally active sigma-1 receptor antagonist with a Ki of 22 nM. EST64454 hydrochloride has the potential for the research of the pain. |
1950569-11-5 |