| DC8338 |
Azeliragon（PF-04494700,TTP488）
Featured
|
Azeliragon is an oral, small-molecule inhibitor of RAGE. |
|
| DC20156 |
Azetidine-2-carboxylic acid
Featured
|
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent. |
|
| DC4210 |
Azilsartan kamedoxomil
Featured
|
Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension. |
|
| DCAPI1469 |
azilsartan
Featured
|
Azilsartan(TAK-536) is a specific and potent angiotensin II type 1 receptor antagonist with IC50 of 2.6 nM. |
|
| DC9818 |
Azoramide
Featured
|
Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. |
|
| DC12497 |
(Z)-Azoxystrobin
Featured
|
Azoxystrobin is a systemic, broad-spectrum fungicide belonging to the class of methoxyacrylates,which are derived from the naturally-occurring strobilurins. |
|
| DC21570 |
Azvudine
Featured
|
Azvudine (RO 0622) is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 24 nM; inhibits RNA synthesis by HCV polymerases from either HCV genotypes 1a and 1b or containing S96T or S282T point mutations (IC50=10-100 nM). |
|
| DC10026 |
B02
Featured
|
B02 is a cell-permeable pyridinylvinyl-quinazolinone compound that is shown to specifically inhibit human RAD51 (IC50 = 27.4 µM). |
|
| DC12033 |
(S)-B-973B
Featured
|
B-973 (B973) is a potent, selective α7 nAChR ago-PAM, denonstrates analgesic effect with attenuating pain behavior and decreasing paw edema in vivo. |
|
| DC10859 |
Baccatin III
Featured
|
Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). |
|
| DC2013 |
Bafetinib (INNO-406)
Featured
|
Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM and 19 nM, respectively. |
|
| DC8858 |
Bafilomycin A1(Baf-A1)
Featured
|
Bafilomycin A1 is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM. |
|
| DC7371 |
Balicatib
Featured
|
Balicatib(AAE-581) is a potent and selective inhibitor of cathepsin K; 10-100-fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S. |
|
| DC11516 |
Balovaptan
Featured
|
Balovaptan (RG7314, RG-7314) is a potent, selective vasopressin-1 receptor antagonist.. |
|
| DC11057 |
Baloxavir acid
Featured
|
Baloxavir acid (S-033447) is an anti-influenza compound that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses. |
|
| DC11056 |
Baloxavir marboxil
Featured
|
Baloxavir marboxil is a prodrug of S-033447. S-033447 is a small molecule inhibitor of the cap-dependent endonuclease of influenza A and B viruses. |
|
| DC8298 |
BAN ORL 24
Featured
|
BAN ORL 24 is a potent, selective, competitive ORL1 non-peptide agonist. Displays 1000-fold selectivity over classical opioid receptors. |
|
| DC10502 |
BAPTA/AM(BAPTA-AM)
Featured
|
BAPTA/AM is a membrane permeable form of BAPTA, a selective chelator of Ca2+. |
|
| DC10385 |
BAR501
Featured
|
BAR501 is a potent and selective agonist of GPBAR1 with an EC50 of 1 μM. |
|
| DC10564 |
BAR 502
Featured
|
BAR502 is a dual FXR and GPBAR1 agonist with IC50 values of 2 μM and 0.4 μM, respectively. |
|
| DC4135 |
Bardoxolone methyl
Featured
|
Bardoxolone methyl (also known as “RTA 402” and “CDDO-methyl ester”) is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. |
|
| DC5064 |
Baricitinib (INCB28050, LY3009104)
Featured
|
Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2,showed potent activity against COVID-19(SARS-COV-2). |
|
| DC8258 |
Baricitinib phosphate
Featured
|
Baricitinib phosphate(INCB 028050; LY 3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2,showed potent activity against COVID-19(SARS-COV-2). |
|
| DC9935 |
Basmisanil(RG1662)
Featured
|
Basmisanil is a highly selective inverse agonist/negative allosteric modulator of α5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome. |
|
| DC10021 |
Batefenterol
Featured
|
Batefenterol（GSK961081，TD-5959）is a Muscarinic Antagonist and β2-Agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA). |
|
| DC8133 |
Batimastat(BB-94)
Featured
|
Batimastat was used to study the role of MMP in proteolytic release of EGF in human follicular thyroid carcinoma cell line FTC-133. |
|
| DC12663 |
Bax channel blocker(BAI-1)
Featured
|
Bax channel blocker is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50 = 0.52 μM). Suggested to inhibit Bax channel formation/activity. |
|
| DC7869 |
BAY11-7082
Featured
|
BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM. Also inhibiting components of the ubiquitin system. |
|
| DC8038 |
Bay 11-7085
Featured
|
BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with an IC50 value of 10 μM. |
|
| DC20589 |
BAY 1251152
Featured
|
BAY 1251152 (VIP152
) is the first potent, selective, orally available PTEFb/CDK9 inhibitor with biochemical IC50 of 9 nM and MOLM13 cell IC50 of 29 nM, displays> 50-fold selectivity against other CDKs. |
|
