An analog of thymoquinone that blocks pSer/pThr recognition by Plk1 Polo-box domain as a phosphate mimic..

An angiotensin II analog that is an agonist of AT1 angiotensin receptor..

An antibiotic that inhibits eukaryotic protein synthesis by inhibiting peptidyl transferase or the 80S ribosome system.

Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine.

An antimicrobial agent used as a substitute for chlorophenols

MMAF-Ome belongs to ADC, and inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.

An E3 ligase ligand-linker conjugate for PROTAC.

An E3 ligase ligand-linker conjugate for PROTAC..

An E3 ligase ligand-linker conjugate for PROTAC..

An E3 ligase ligand-linker conjugate for PROTAC..

An E3 ligase ligand-linker conjugate for PROTAC.

LE135 is a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels.

An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids.

An immunoactive peptide that has been shown to inhibit cell proliferation and induce apoptosis in human leukemia, non-small cell lung cancer, melanoma, and other human cancers.

An immunosuppressive agent and macrolide antibiotic.

IRES-J007 ia an improved IRES inhibitor that blocks IRES-hnRNP A1 binding; binds to a small pocket structure within the RRM-containing fragment of hnRNP A1 (UP1 fragment), inhibits cyclin D1 and c-MYC IRES activity to a greater extent compared with C11 (IRES-C11); significantly reduces tumor growth of GBM xenografts in mice, and markedly reduces the mRNA translational state of cyclin D1 and c-MYC transcripts combined with PP242.

An inhibitor of LPS-induced TNFαrelease.Pomalidomide is thalidomide derivative that displays inhibition of LPS-induced TNFα release. Shows immunomodulator and anticancer effects.

An insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells.

An irreversible, dual EGFR/HER2 inhibitor with IC50 of 0.5/0.4/10/14 nM for wt EGFR/EGFR L858R/EGFR L858R+T790M/HER2 respectively.

PK 11195 is a ligand of translocator protein. It targets Leishmania chemotherapy (IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively).

Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1.

An orally active adenosine receptor agonist that can induce acute cardiovascular toxicity and coronary vascular injury in vivo..