Cat. No. | Product name | CAS No. |
DC65109 | 3-(Chloromethyl)-1-methyl-1H-1,2,4-triazole hydrochloride Featured | 135206-76-7 |
DC65110 | 3-(Chloromethyl)-1-methyl-1H-1,2,4-triazole Featured | 233278-54-1 |
DC65111 | CPD101077-B HCl Featured | 1948273-01-5 |
DC65112 | 5-Chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-amine Featured | 1832583-43-3 |
DC85555 |
YK009
Featured
YK-009 is a novel ionizable lipid for mRNA delivery. Comparisons of YK009-LNP-mRNA and commercial MC3-LNP-mRNA showed that YK009-LNP-mRNA vaccines had good biodistribution patterns, favorable tissue clearance, and high delivery efficiency. Furthermore, our study proved that YK009-LNP-Omicron mRNA could trigger a robust immune response and immune protection against the SARS-CoV-2 Omicron variant. |
2761458-86-8 |
DC85600 |
Lipidoid S14
Featured
Lipidoid S14 is a novel lipidoid for siRNA delivery.Lipidoid-polymer hybrid nanoparticle (FS14-NP) can efficiently deliver siRNA against IL-1β (siIL-1β) to macrophages and effectively suppress the pathogenesis of experimental arthritis induced by collagen antibody (CAIA mice). FS14-NP/siIL-1β achieved approximately 70% and 90% gene-silencing efficiency in the RAW 264.7 cell line and intraperitoneal macrophages, respectively. Intravenous administration of FS14-NP/siRNA led to rapid accumulation of siRNA in macrophages within the arthritic joints. Furthermore, FS14-NP/siIL-1β treatment lowered the expression of pro-inflammatory cytokines in arthritic joints and dramatically attenuated ankle swelling, bone erosion, and cartilage destruction. |
2349307-29-3 |
DC65115 | 2-Fluoro-3-(methylsulfonyl)aniline Featured | 1335496-06-4 |
DC65116 | 2-Aminopyrazolo[1,5-A]pyrimidine-3-carboxylic acid Featured | 1394003-86-1 |
DC65117 | SJ-07 Featured | 130263-10-4 |
DC65118 | SJ-06 Featured | 137760-69-1 |
DC65119 | SJ-05 Featured | 188546-66-9 |
DC65120 | SJ-04 Featured | 2639833-10-4 |
DC65121 | SJ-03 Featured | 82017-78-5 |
DC65122 | tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate Featured | 1174020-44-0 |
DC60443 |
PYR01
Featured
Pyr01 is a targeted activator of cell kill (TACK) and shows more than 300-fold more potent than doravirine and also retains reverse transcriptase (RT) inhibition activity within about 3-fold of doravirine. |
2560576-15-8 |
DC65123 | (R)-1-(3-Nitro-5-(trifluoromethyl)phenyl)ethan-1-amine hydrochloride Featured | 2230840-47-6 |
DC65124 | 1,2-Benzenediamine, 4-[6-(dimethylamino)-4-pyrimidinyl]- Featured | 2409479-30-5 |
DC65125 | CPD2500-A3 Featured | 1239510-82-7 |
DC65126 | Potassium (4-Boc-piperazin-1-yl)methyltrifluoroborate Featured | 936329-97-4 |
DC65127 | (αR)-α-Methyl-N-(2,2,2-trifluoroethyl)-1H-indole-3-ethanamine Featured | 1953133-30-6 |
DC65128 | 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE Featured | 374930-88-8 |
DC65129 | CPD3325-A8 Featured | 1352609-91-6 |