DC10672 |
DNQX
Featured
|
DNQX is a elective non-NMDA antagonist |
|
DC11464 |
DO-264
Featured
|
DO264 is an inhibitor of α/β-hydrolase domain-containing protein 12 (ABHD12; IC50 = 11 nM).It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells. |
|
DC4187 |
Docetaxel
Featured
|
Docetaxel, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules. |
|
DC9648 |
Dodecanoic acid ingenol ester
Featured
|
Dodecanoic acid ingenol ester is a natural compound. |
|
DC12216 |
Dodecanoylcarnitine
Featured
|
Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. |
|
DCAPI1022 |
Dofetilide (Tikosyn)
Featured
|
Dofetilide (Tikosyn) |
|
DC7273 |
Dolutegravir
Featured
|
Dolutegravir (DTG, GSK1349572) is an integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. |
|
DC10250 |
Dolutegravir Sodium
Featured
|
Dolutegravir is a HIV integrase inhibitor with IC50 of 2.7 nM. |
|
DC3155 |
Donepezil hydrochloride
Featured
|
Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively. |
|
DC11103 |
Tavapadon
Featured
|
Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors. |
|
DC9308 |
Doravirine (MK-1439)
Featured
|
Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor. |
|
DC7115 |
Dorsomorphin dihydrochloride
Featured
|
Dorsomorphin 2Hcl (Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; also inhibits ALK2, ALK3, and ALK 6 . |
|
DC3142 |
Dovitinib Dilacticacid
Featured
|
Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively. |
|
DC4157 |
Dovitinib (TKI258, CHIR258)
Featured
|
Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively. |
|
DC3141 |
Dovitinib (TKI258) Lactate
Featured
|
Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively. |
|
DC9664 |
Doxapram
Featured
|
Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively. |
|
DCAPI1241 |
Doxercalciferol (Hectorol)
Featured
|
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease. |
|
DC4188 |
Doxorubicin hydrochloride
Featured
|
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
|
DC8383 |
Dp44mT
Featured
|
Dp44mT is a potent iron chelator, which shows selective antitumor activity. |
|
DC20966 |
DPM-1001
Featured
|
DPM-1001 is a potent, selective, orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B with IC50 of 100 nM, also chelates copper, which enhanced its potency as a PTP1B inhibitor. |
|
DC9949 |
DprE1-IN-2
Featured
|
DprE1-IN-2 is a potent DprE1 inhibitor. |
|
DC11173 |
DRAinh-A250
Featured
|
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
|
DC10039 |
DREADD Agonist 21
Featured
|
DREADD agonist 21 is a potent muscarinic hM3Dq DREADD agonist (EC50 = 1.7 nM). Highly selective for hM3Dq DREADDs over endogenous hM3 receptors. |
|
DC20103 |
D-Ribose(mixture of isomers)
Featured
|
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation |
|
DCAPI1562 |
Drospirenone
Featured
|
Drospirenone is a synthetic progestogen exhibiting antiandrogenic and antimineralocorticoid activity. |
|
DC2056 |
Droxidopa (L-DOPS,SM-5688)
Featured
|
Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). |
|
DC8350 |
Droxinostat
Featured
|
Droxinostat is a selective HDAC3, HDAC6 and HDAC8 inhibitor. |
|
DC20975 |
DS-2330
Featured
|
DS-2330 is a phosphorous lowering agent for treating hyperphosphatemia in chronic kidney disease.. |
|
DC11726 |
Milademetan
Featured
|
Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis. |
|
DC12410 |
8-{1-[(1R,4R)-4-aminocyclohexyl]ethenyl}-5,5-dimethyl-5,6-dihydrobenzo[h]quinazolin-4-amine
Featured
|
DS42450411 (DS 42450411, DS-42450411) is a potent, orally active hepcidin production inhibitor with IC50 of 32 nM. |
|