Cat. No. | Product name | CAS No. |
DC10770 |
CU-CPT-9a
Featured
CU-CPT9a is an antagonist of toll-like receptor 8 (TLR8). It inhibits activation of NF-κB induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells (IC50 = 0.5 nM). CU-CPT9a reverses R-848-induced increases in NF-κB p65, IRAK-4, and TRAF3 protein levels in HEK-Blue cells. |
2165340-32-7 |
DC9282 |
cucurbitacin B
Featured
Cucurbitacin B, an oxygenated tetracyclic triterpenoid compound extracted from Cucurbitaceae plant species, is a long-term anticancer agent by disruption of microtubule polymerization. |
6199-67-3 |
DC23035 |
Curcurbitacin IIa
Featured
Cucurbitacin IIa has anti-cancer, anti-bacterial, and anti-inflammatory effects, it can induce apoptosis and enhance autophagy; it also can disrupt the actin cytoskeleton and direct the cell to undergo PARP-mediated apoptosis through the inhibition of sur |
58546-34-2 |
DC7544 |
CUDC-101
Featured
CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1. |
1012054-59-9 |
DC9699 |
CVM-1118(CVM1118)
Featured
CVM-1118(CVM1118) has high anti-cancer activity, good safety margin, and multiple mechanisms of action targeting cancer, especially its unique ability to inhibit vasculogenic mimicry (VM). |
1256037-58-7 |
DC7391 |
CVT-10216
Featured
CVT-10216 is a potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively). |
1005334-57-5 |
DC9306 |
CVT-313(NG-26)
Featured
CVT-313(NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 (IC50 = 0.5 uM for Cdk2/A and Cdk2/E; 4.2 uM for Cdk1/B; 215 uM for Cdk4/D1). |
199986-75-9 |
DC7392 |
CW069
Featured
CW-069 is a novel and allosteric inhibitor of the microtubule motor protein HSET with IC50 value of 75 ± 20 μM; shows statistically significant selectivity over KSP. |
1594094-64-0 |
DC9278 |
CWHM-12
Featured
CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1. |
1564286-55-0 |
DC7111 |
CX-4945 (Silmitasertib)
Featured
CX-4945 (Silmitasertib) is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively. |
1009820-21-6 |
DC23942 |
CX-4945 sodium salt(Silmitasertib)
Featured
CX-4945 Sodium Salt is a water soluble CX-4945 (GLXC-04060), First-in-class Casein kinase 2 (CK2) inhibitor, sequentially attenuating the proteins in PI3K/Akt and MAPK pathways. |
1309357-15-0 |
DC24074 |
CX-546
Featured
CX546 is an AMPA receptor potentiator and GluR activator, binds specifically to the agonist bound non-desensitized receptor. |
215923-54-9 |
DC7810 |
CX-5461
Featured
CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA, has no effect on Pol II, and possesses 250-to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. |
1138549-36-6 |
DC7153 |
CX6258
Featured
CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity. |
1202916-90-2 |
DC9925 |
CXD101(AZD-9468)
Featured
CXD101(AZD-9468) is a novel histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. |
934828-12-3 |
DC10620 |
CY-09
Featured
CY-09 is an NLRP3 inhibitor. |
1073612-91-5 |
DC10576 |
Cyantraniliprole
Featured
Cyantraniliprole(HGW-86) is an insecticide of the ryanoid class; has activity against pests such as Diaphorina citri that have developed resistance to other classes insecticides. |
736994-63-1 |
DC10442 |
Cyazofamid
Featured
Cyazofamid is a foliar fungicide approved for use in the EU. |
120116-88-3 |
DC10775 |
Fadraciclib (CYC065)
Featured
CYC065 is an orally bioavailable inhibitor of cyclin dependent kinases 2, 5 and 9 (CDK2/5/9) with potential antineoplastic and chemoprotective activities. |
1070790-89-4 |
DC7325 |
CYC116
Featured
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM. |
693228-63-6 |
DC10541 |
Cyclo(RGDfC)
Featured
Cyclo (RGDfC), avb3 Integrin Binding Cyclic RGD Peptide,This is a cyclic RGDfC sequence, an integrin avb3-affine peptide. |
862772-11-0 |
DC26050 |
Cyclo(L-Pro-L-Val)
Featured
Cyclo(L-Pro-L-Val) is a diketopiperazine that has been found in the marine sponge T. ignis, the bacterium B. pumilus, and the fungus A. fumigatus, among others. |
2854-40-2 |