GPCR

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Cat. No.	Product Name	Field of Application
DC10924	BMS986202 Featured	BMS-986202 is a clinical Tyk2 inhibitor that binds to Tyk2 JH2 with IC50 of 0.19 nM and shows remarkably selectivity over other kinases including Jak family members.
DC9937	BMT-145027	BMT-145027 is a potent mGluR5 PAM with no inherent mGluR5 agonist activity.
DC7377	BMY 7378 Featured	BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.
DC9437	Bosentan	Bosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
DCAPI1483	Bosentan Hydrate	Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
DC8883	BP897 Featured	BP897 is a partially selective D3 dopamine receptor agonist.
DC10618	BPTU Featured	BPTU is an Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM).
DC8392	BQ-123 Featured	BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
DC10338	Bradykinin	Bradykinin is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions.
DC7097	Cebranopadol(GRT-6005) Featured	branopadol(GRT-6005) is a novel first in class compounds with potent agonist activity on ORL-1 (opioid receptor like -1) and the well established mu opioid receptor.
DC8286	Brexpiprazole(OPC34712) Featured	Brexpiprazole is a novel D2 dopamine partial agonist.
DC7888	BRL54443	BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors.
DC7091	BRL-15572 dihydrochloride	BRL-15572 2Hcl is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.
DC9141	Brompheniramine hydrogen maleate	Brompheniramine maleate is a histamine H1 receptors antagonist.
DC10954	BS148	BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1.
DC10945	BU09059	BU09059 is a potent, selective, short-acting kappa-opioid receptor antagonist with Ki of 1.72 nM, displays 15- and 616-fold selectivity over μ- and δ-receptors respectively.
DC10693	O-Butyryl timolol Featured	Butyryltimolol is a lipophilic ester prodrug of timolol, a beta adrenergic blocer with antihypertensive and hemodynamic properties.
DC7675	BX-471（ZK 811752） Featured	BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1); exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
DC9423	Cabergoline	Cabergoline, an ergot derivative, is a potent dopamine receptor agonist on D2 receptors.
DC9386	Calcium-Sensing Receptor Antagonists I	Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors.
DC9185	Candesartan cilexetil Featured	Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
DC9142	Candesartan	Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.
DC7005	Cangrelor free acid Featured	Cangrelor is a P2Y12 inhibitor, and was approved in June 2015 as an antiplatelet drug for intravenous application. Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggrega
DC10222	CarbinoxaMine Maleate	Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties.
DC8054	Cariprazine (RGH-188) Featured	Cariprazine (RGH-188) is a novel putative antipsychotic drug that exerts partial agonism at dopamine D2/D3 receptors, with preferential binding to D3 receptors, and partial agonism at serotonin 5-HT1A receptors.
DC11354	Carteolol (hydrochloride)	Carteolol is an antagonist of β-adrenergic receptors (Kd = 13 nM).
DC10847	CAY10441（RO1138452） Featured	CAY10441 is a Selective prostacyclin IP receptor antagonist.
DC12099	CAY10595	CAY10595 is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki of 10 nM.
DC11204	CCR6 inhibitor 35	CCR6 inhibitor 35 is a potent and selective CCR6 inhibitor with IC50 of 6.0 nM (hCCR6).
DC10206	CCX140	CCX140 is a potent CCR2 antagonist.

GPCR

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