| DCAPI1536 |
Cyproheptadine Hydrochloride |
Cyproheptadine hydrochloride is a migraine prophylactic and Non-selective SR-2A (5HT2) antagonist. Cyproheptadine hydrochloride is an inhibitor of Histamine H1 Receptor and SR-2C. |
|
| DC11124 |
D-520 |
D-520 is a potent, multifunctional D2/D3 agonist with Ki of 41.8 /0.35 nM, modulates aggregation of alpha-synuclein (αSN) and reduces toxicity of preformed aggregates of αSN. |
|
| DC9689 |
Danirixin (GSK1325756)
Featured
|
Danirixin(GSK1325756) is a selective CXCR2 antagonist. |
|
| DC12498 |
S-Darusentan
Featured
|
Darusentan is a potent inhibitor of endothelin signaling and function in both large and small arteries. |
|
| DC7790 |
CB1-IN-1(BPRCB1184)
Featured
|
CB1-IN-1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0.3 nM (Ki, CB1R) 21 nM (Ki, CB2R) Target: CB1R in vivo: CB1-IN-1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice. CB1-IN-1 has great potential to ameliorate this related metabolic syndrome. |
|
| DC10554 |
DC260126
Featured
|
DC260126, a small-molecule antagonist of GPR40. |
|
| DC9057 |
Desloratadine |
Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies. |
|
| DC8097 |
Detomidine hydrochloride |
Detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist |
|
| DC4240 |
Dexmedetomidine hydrochloride
Featured
|
Dexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties. |
|
| DC4161 |
Dimebon dihydrochloride |
Dimebon is an antihistamine drug. |
|
| DC9863 |
Dinoprost
Featured
|
Dinoprost(Prostaglandin F2α) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. |
|
| DCAPI1702 |
Diphemanil methylsulfate
Featured
|
Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR). |
|
| DC10683 |
DL 071-IT hydrochloride |
DL 071-IT is a potent non-selective beta-adrenoceptor antagonist. |
|
| DC9323 |
Dalasetron (Mesylate hydrate) |
Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. |
|
| DC11103 |
Tavapadon
Featured
|
Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors. |
|
| DC9109 |
Doxylamine succinate |
Doxylamine is a first generation antihistamine; can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief. |
|
| DC10039 |
DREADD Agonist 21
Featured
|
DREADD agonist 21 is a potent muscarinic hM3Dq DREADD agonist (EC50 = 1.7 nM). Highly selective for hM3Dq DREADDs over endogenous hM3 receptors. |
|
| DC11233 |
DS-8500a |
DS-8500a (DS8500a) is a novel potent, selective, orally available GPR119 agonist with EC50 of 51.5 nM in human GPR119-expressing CHO-K1 cells, displays no significant effect on 66 receptors, channels, or transporters. |
|
| DC8533 |
E5555 hydrobromide |
E5555 shows potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC values of 0.064 and 0.031 μM respectively. |
|
| DC10563 |
E-7046
Featured
|
E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities. |
|
| DC8323 |
Eletriptan HBr
Featured
|
Eletriptan HBr is an orally active, selective 5-HT1B/1D receptor agonist. |
|
| DC7772 |
Elinogrel |
Elinogrel is a reversible P2Y12 receptor antagonist for the treatment of acute coronary syndrome and prevention of secondary thrombotic events. |
|
| DC8626 |
Eluxadoline
Featured
|
Eluxadoline is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist. |
|
| DC10869 |
Olodanrigan(EMA401)
Featured
|
EMA401(Olodanrigan) is a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. |
|
| DC11028 |
EMD-281014 hydrochloride |
EMD-281014 hydrochloride is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
|
| DC11027 |
EMD-281014 |
EMD-281014 is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
|
| DC9467 |
Epinastine
Featured
|
Epinastine(WAL801) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
|
|
| DC9260 |
Eptapirone
Featured
|
Eptapirone (F-11,440) is a very potent and highly selective 5-HT1A receptor full agonist of the azapirone family. |
|
| DC9016 |
Etamsylate |
Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins. |
|
| DC10040 |
Etrasimod(APD334)
Featured
|
Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1(S1P1) receptor with an IC50 value of 1.88 nM in CHO cells. |
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