| DCAPI1535 |
Etodolac |
Etodolac is a Cox-2 inhibitor with anti-inflammatory and analgesic activity. Etodolac is shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of ab |
|
| DC10239 |
Etoricoxib
Featured
|
Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
|
| DC8917 |
Firocoxib |
Firocoxib(ML 1785713) is a potent and selective cyclooxygenase (COX)-2 inhibitor with IC50 of 0.13 uM, 58 fold sensitivity for COX2 VSCOX1. |
|
| DC7112 |
FK 3311
Featured
|
FK 3311 is a selective inhibitor of COX-2; antiinflammatory agent. |
|
| DCAPI1206 |
Flurbiprofen (Ansaid) |
Flurbiprofen (Ansaid) |
|
| DC3154 |
Fingolimod HCl（FTY-720）
Featured
|
FTY720 (Fingolimod, Gilenya) is a S1P antagonist with IC50 of 0.033 nM. |
|
| DC10876 |
H-151
Featured
|
H-151(H151) is a novel STING (stimulator of interferon genes) antagonist. |
|
| DC7424 |
HPGDS-inhibitor-1
Featured
|
HPGDS inhibitor 1 is a novel and selective Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50 Value of 0.7 nM. |
|
| DC8965 |
Ibuprofen |
Ibuprofen (Motrin) is an anti-inflammatory inhibitor targeting COX-1 and COX-2, of which is used for pain relief, fever reduction and for reducing swelling. |
|
| DC10730 |
Inarigivir(ORI-9020,SB-9000)
Featured
|
Inarigivir(SB-9000) is a novel dinucleotide, evaluated in transgenic mice expressing hepatitis B virus (HBV), significantly reduced liver HBV DNA。 |
|
| DC10483 |
INF39
Featured
|
INF39 is an irreversible and noncytotoxic NLRP3 inhibitor. |
|
| DC8328 |
IRAK-1/4 Inhibitor
Featured
|
Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor is a benzimidazole compound that acts as a cell-permeable, potent selective inhibitor of IL-1 kinases. |
|
| DC9491 |
IRAK inhibitor 1
Featured
|
IRAK inhibitor 1 is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. |
|
| DC9492 |
IRAK inhibitor 2 |
IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor . |
|
| DC10584 |
IRAK4-IN-1
Featured
|
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM. |
|
| DC7609 |
Isatoribine |
Isatoribine is a selective agonist of TLR7 |
|
| DC9100 |
Ketorolac Tromethamine |
Ketorolac (Ketorolac tromethamine, Toradol) is a non-selective COX inhibitor with strong analgesic activity. |
|
| DC9953 |
Leukadherin-1
Featured
|
Leukadherin-1 is a specific agonist of CR3 and the leukocyte surface integrin CD11b/CD18. |
|
| DC8751 |
Licofelone |
Licofelone is a dual COX/LOX inhibitor being considered as a treatment for osteoarthritis. |
|
| DCAPI1208 |
L-NAME HCl |
L-NAME is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively. |
|
| DCAPI1565 |
Loxoprofen Sodium |
Loxoprofen is a non-steroidal anti-inflammatory drug that is quickly converted to the trans-alcohol metabolite. It is similar to ibuprofen and naproxen, while also being a Cycloxygenase (COX) inhibitor. |
|
| DC9938 |
Lusutrombopag（S-888711）
Featured
|
Lusutrombopag（S-888711） is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist being developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. |
|
| DC7651 |
MF63
Featured
|
MF63 is a selective mPGES-1 inhibitor with an IC50 of 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively. |
|
| DC9448 |
MK591 |
MK591(Quiflapon sodium) is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor. |
|
| DC10908 |
ML RR-S2 CDA
Featured
|
ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING). |
|
| DC10142 |
ML130
Featured
|
ML-130 is a potent and selective inhibitor of NOD1; displays 36-fold selectivity for NOD1 over NOD2 (IC50 values are 0.56 and >20 μM for NOD1 and NOD2 respectively). |
|
| DC9000 |
Naproxen sodium |
Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively. |
|
| DC8982 |
Naproxen |
Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively. |
|
| DCAPI1342 |
Nepafenac |
Nepafenac |
|
| DC9930 |
NOD-IN-1
Featured
|
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively. |
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