DCC3714 |
Nplc0393 |
Novel inhibitor of TGF-β1 signaling pathway, inhibiting the upregulation of MAT2A mechanistically, dose-dependently activating PP2Cα and efficiently alleviating liver fibrosis |
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DCC3715 |
Npr-c Activator 1 |
Novel potent activator of the natriuretic peptide receptor C (NPR-C) with EC 50 ~1 μM |
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DCC3716 |
Nps-89636 |
Calcilytic negative allosteric modulator of calcium-sensing receptor (CaR) |
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DCC3717 |
Nqo1 Substrate 1 |
Novel substrate for NAD(P)H: quinone oxidoreductase 1 (NQO1), acting as an effective intracellular ROS generator for the treatment of drug-resistant non-small-cell lung cancer |
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DCC3718 |
Nr2b-in-1 |
Novel NMDA/NR2B Antagonist |
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DCC3719 |
Nrf2/ho-1 Activator Ll202 |
Novel activator of the Nrf2/HO-1 pathway, upregulating heme oxygenase-1 (HO-1) via promoting nuclear translocation of nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) to regulate LPS‐induced oxidative stress in macrophages |
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DCC3720 |
Nrf2-activator
Featured
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Nrf2-Activator is a potent Nrf-2 activator. |
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DCC3721 |
Ns-0011 |
Novel inhibitor of CDK5 translocation, increasing CDK5 accumulation in the nucleus, suppressing both cancer cell proliferation and xenograft tumorigenesis. |
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DCC3722 |
Ns-2710 |
Potent, non-selective partial agonist at GABAA receptors with little efficacy at the alpha1 subtype and more at alpha2 and alpha3 |
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DCC3723 |
ns3/4a-in-12 |
Novel Inhibitor with Activity against NS3/4A proteases from Multiple Hepatitis C Virus Genotypes |
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DCC3724 |
ns3-in-5 |
Novel allosteric inhibitor of HCV NS3 protein function |
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DCC3725 |
Ns4591 |
Novel molulator of SK-IK channels [small- and intermediate-conductance Ca2(+) -activated K(+) channels] |
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DCC3726 |
Ns-6740 |
Novel potent α7 nAChR partial agonist |
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DCC3727 |
Ns-6784 Hydrochloride |
Novel α7 nAChR agonist at human and rat receptors |
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DCC3728 |
Nsc10010 |
Novel potent growth inhibitor for gammaherpesvirus-associated B-lymphomas through activation of both the NF-κB and c-Myc-mediated signaling pathways |
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DCC3729 |
Nsc1008 |
Novel Inhibitor of the Ras Converting Enzyme 1 (Rce1) Protease, Disrupting Ras Membrane Localization in Human Cells |
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DCC3730 |
Nsc-100874 |
Novel antagonist of the Grb7 SH2 domain; Antitumor Agent |
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DCC3731 |
Nsc1011 |
Ras converting enzyme 1 (Rce1) inhibitor |
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DCC3732 |
Nsc103054 |
Novel inhibitor of ABCG2 transporter function |
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DCC3733 |
Nsc-104999 |
Ligand of the Grb7 SH2 domain, inhibiting the growth of MDA-MB-468 cancer cells |
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DCC3734 |
Nsc107392 |
Novel substrate of ABCG2 |
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DCC3735 |
Nsc109131 |
Inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1) |
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DCC3736 |
Nsc109779 |
Novel potent inhibitor of Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein |
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DCC3737 |
Nsc114792 |
Novel selective inhibitor of JAK3 |
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DCC3738 |
Nsc-117199 |
Selective inhibitor of shp2 protein tyrosine phosphatase (PTP) |
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DCC3739 |
Nsc-12404 |
Selective non-lipid agonist of LPA2/3 |
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DCC3740 |
Nsc-126188 |
Apoptosis inducer; Antitumor agent |
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DCC3741 |
Nsc127133 |
Novel inhibitor of the second bromodomain (BD2) of the BET family protein BRD2 |
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DCC3742 |
Nsc-13030 |
Novel potent SHP2 Inhibitor with Anti-Proliferative Activity in Breast Cancer Cell Lines |
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DCC3743 |
Nsc-134754 |
HIF-pathway inhibitor |
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