| DC7098 |
BI-D1870
Featured
|
BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC50s are 31 nM, 24 nM, 18 nM, 15 nM, respectively. |
|
| DC7086 |
BIIB021(CNF2024)
Featured
|
BIIB021(CNF2024) is an orally available, fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectively. |
|
| DC20791 |
BIIL260 |
BIIL260 is the active metabolite of BIIL284, shows high affinity to LTB4 receptor on isolated human neutrophil cell membranes with Ki of 1.7 nM. |
|
| DC8263 |
Bikinin
Featured
|
Bikinin is a strong activator of brassinosteroid (BR) signaling. |
|
| DC7995 |
Bilastine
Featured
|
Bilastine is a selective histamine H1 receptor antagonist used for treatment of allergic rhinoconjunctivitis and urticaria. |
|
| DC20793 |
BILH-434 |
BILH-434 is a potent HPV11 E1/E2/DNA complex inhibitor that binds to the transactivation domain (TAD) of E2 protein with a Kd of 40 nM, has an IC50 of 180 nM in the E1-E2-ori complex formation assay.. |
|
| DC22281 |
Bilobalide
Featured
|
Bilobalide is a sesquiterpene lactone which is found in extracts of G. biloba. |
|
| DCAPI1079 |
Bimatoprost
Featured
|
Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. |
|
| DC6801 |
Bindarit
Featured
|
Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8. |
|
| DC7663 |
BIO
Featured
|
BIO (6-bromoindirubin-3'-oxime) is a specific inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β, shows >16-fold selectivity over CDK5, also a pan-JAKinhibitor. |
|
| DC20795 |
BIO 8898 |
BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM. |
|
| DC11178 |
BIO1211 |
BIO1211 (BIO-1211) is a potent, highly specific integrin α4β1 (VLA-4) inhibitor with Kd/IC50 of 20 pM/4 nM for the activated form of α4β1. |
|
| DC11069 |
BIO124 |
BIO124 (BIO-124) is a modest inhibitor of the PICK1-GluA2 interaction with IC50 of 0.51 uM in FP assays, binds to the PDZ domain of PICK1.. |
|
| DC12401 |
BIO922 |
BIO922 (BIO 922, BIO-922) is a small molecule PICK1 inhibitor that specificly blocks the PDZ domain-mediated interaction between GluA2 and PICK1 (IC50=69 nM), blocks the effects of Aβ on synaptic transmission and surface receptors. |
|
| DC8368 |
BIO-acetoxime
Featured
|
BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO |
|
| DC20320 |
Bio-AMS |
Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM. |
|
| DC7603 |
Bioymifi
Featured
|
Bioymifi(DR5 Activator) is the first novel and potent small-molecule activatior of the TRAIL receptor DR5 in human cancer cells. |
|
| DC25079 |
Biperiden hydrochloride
Featured
|
Biperiden Hcl (NSC 170950, NSC 84989) is a centrally-acting antiparkinsonian agent that functions as a selective central M1 cholinoreceptors blocker.. |
|
| DC7836 |
Doramapimod (BIRB-796)
Featured
|
BIRB 796 (Doramapimod) is a highly selective p38α MAPK inhibitor with Kd of 0.1 nM, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2, ZAP-70, EGFR, HER2, PKA, PKC, PKCα/β/γ. |
|
| DC5023 |
Birinapant (TL32711)
Featured
|
Birinapant (TL32711) is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM, less potent to XIAP. |
|
| DC10863 |
Bis(tributylammonium) difluoromethylenediphosphonate
Featured
|
Bis(tributylammonium) difluoromethylenediphosphonate |
|
| DC10434 |
Bisantrene
Featured
|
Bisantrene is a highly effective antitumor drug, targets eukaryotic type II topoisomerases. |
|
| DC10504 |
BISF-3
Featured
|
BISF CAS 118511-97-0 |
|
| DC10052 |
Bisindolylmaleimide X(Ro 31-8425)
Featured
|
Bisindolylmaleimide X is a cell-permeable, reversible, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 15 nM, rat brain PKC). |
|
| DC8504 |
Bisindolylmaleimide X HCl
Featured
|
Bisindolylmaleimide X is a cell-permeable, reversible, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 15 nM, rat brain PKC). |
|
| DC20798 |
Bisperoxovanadium |
Bisperoxovanadium (bpV(phen) potassium hydrate) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 =38 nM), also inhibits the vascular endothelial PTP, PTP-β (IC50=3 |
|
| DC20212 |
Bisphenol A |
Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It exhibits estrogen-mimicking, hormone-like properties. |
|
| DC21599 |
Bis-T-23 |
Bis-T-23 is a small molecule that stimulates actin-dependent dynamin oligomerization and promotes dynamin GTPase activity, increases actin polymerization in injured podocytes. |
|
| DC11307 |
Bitertanol |
Bitertanol is a broad-spectrum triazole fungicide that is active against a variety of fungi, including V. inaequalis and V. pirina. |
|
| DC8882 |
Bitopertin
Featured
|
Bitopertin, also known as RG1678, is a potent and selective inhibitor of GlyT1 with an EC50 of 30nM. |
|
