| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC20788 | BIBO-3304 Featured | BIBO 3304 is a potent, selective, nonpeptide neuropeptide Y Y1 receptor antagonist with IC50 of 0.38 and 0.72 nM for human and the rat Y1 receptor, respectively. |
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| DC12211 | BIBR 1087 SE (Desethyl Dabigatran Etexilate) | BIBR 1087 SE is an intermediate metabolite of dabigatran etexilate. |
|
| DC7085 | BIBR-1532 Featured | BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM. |
|
| DCAPI1112 | BIBR 953(Dabigatran) Featured | BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. |
|
| DC1010 | BIBR-1048 (Dabigatran etexilate) Featured | BIBR-1048 (Dabigatran) is an anticoagulant from the class of the direct thrombin inhibitors. |
|
| DC9670 | BIBS39 Featured | BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. |
|
| DC20789 | BIBU1361 | BIBU1361 is a potent, selective, orally active EGFR inhibitor with IC50 of 3 nM, shows weak activity against HER2 (IC50=280 nM) and no inhibition on IGF1R, HGFR, Src, and VEGFR2 (IC50>10 uM). |
|
| DC20790 | BIBU1361 dihydrochloride | BIBU1361 is a potent, selective, orally active EGFR inhibitor with IC50 of 3 nM, shows weak activity against HER2 (IC50=280 nM) and no inhibition on IGF1R, HGFR, Src, and VEGFR2 (IC50>10 uM). |
|
| DC1024 | Afatinib (BIBW2992) Featured | BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively. |
|
| DC10890 | Bictegravir Featured | Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. |
|
| DC10393 | Bicyclomycin benzoate | Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium. |
|
| DC7098 | BI-D1870 Featured | BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC50s are 31 nM, 24 nM, 18 nM, 15 nM, respectively. |
|
| DC7086 | BIIB021(CNF2024) Featured | BIIB021(CNF2024) is an orally available, fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectively. |
|
| DC20791 | BIIL260 | BIIL260 is the active metabolite of BIIL284, shows high affinity to LTB4 receptor on isolated human neutrophil cell membranes with Ki of 1.7 nM. |
|
| DC8263 | Bikinin Featured | Bikinin is a strong activator of brassinosteroid (BR) signaling. |
|
| DC7995 | Bilastine Featured | Bilastine is a selective histamine H1 receptor antagonist used for treatment of allergic rhinoconjunctivitis and urticaria. |
|
| DC20793 | BILH-434 | BILH-434 is a potent HPV11 E1/E2/DNA complex inhibitor that binds to the transactivation domain (TAD) of E2 protein with a Kd of 40 nM, has an IC50 of 180 nM in the E1-E2-ori complex formation assay.. |
|
| DC22281 | Bilobalide Featured | Bilobalide is a sesquiterpene lactone which is found in extracts of G. biloba. |
|
| DCAPI1079 | Bimatoprost Featured | Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. |
|
| DC6801 | Bindarit Featured | Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8. |
|
| DC7663 | BIO Featured | BIO (6-bromoindirubin-3'-oxime) is a specific inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β, shows >16-fold selectivity over CDK5, also a pan-JAKinhibitor. |
|
| DC20795 | BIO 8898 | BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM. |
|
| DC11178 | BIO1211 | BIO1211 (BIO-1211) is a potent, highly specific integrin α4β1 (VLA-4) inhibitor with Kd/IC50 of 20 pM/4 nM for the activated form of α4β1. |
|
| DC11069 | BIO124 | BIO124 (BIO-124) is a modest inhibitor of the PICK1-GluA2 interaction with IC50 of 0.51 uM in FP assays, binds to the PDZ domain of PICK1.. |
|
| DC12401 | BIO922 | BIO922 (BIO 922, BIO-922) is a small molecule PICK1 inhibitor that specificly blocks the PDZ domain-mediated interaction between GluA2 and PICK1 (IC50=69 nM), blocks the effects of Aβ on synaptic transmission and surface receptors. |
|
| DC8368 | BIO-acetoxime Featured | BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO |
|
| DC20320 | Bio-AMS | Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM. |
|
| DC7603 | Bioymifi Featured | Bioymifi(DR5 Activator) is the first novel and potent small-molecule activatior of the TRAIL receptor DR5 in human cancer cells. |
|
| DC23078 | Biperiden Featured | Biperiden (KL 373) is a centrally-acting antiparkinsonian agent that functions as a selective central M1 cholinoreceptors blocker.. |
|
| DC25079 | Biperiden hydrochloride Featured | Biperiden Hcl (NSC 170950, NSC 84989) is a centrally-acting antiparkinsonian agent that functions as a selective central M1 cholinoreceptors blocker.. |
|
