| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC22437 | Burimamide oxalate | Burimamide oxalate is a potent dual H3/H2 receptor antagonist with Ki of 0.07 and 7.8 uM, respectively. |
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| DC20059 | Burixafor hydrobromide (TG-0054 hydrobromide) | Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization. Burixafor hydrobromide (TG-0054 hydrobr |
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| DC8995 | Busulfan/Myleran | Busulfan is a bifunctional alkylating agent. |
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| DCAPI1407 | Butenafine | Butenafine |
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| DC10693 | O-Butyryl timolol Featured | Butyryltimolol is a lipophilic ester prodrug of timolol, a beta adrenergic blocer with antihypertensive and hemodynamic properties. |
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| DC7563 | BV6 Featured | BV6 induced apoptotic and necrotic cell death in monocytes while T-cells, dendritic cells and macrophages were largely protected against BV6-induced cell death. |
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| DC8089 | BVT 2733(BVT.2733) Featured | BVT 2733 is a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor,protecting osteoblasts against endogenous glucocorticoid induced dysfunction. |
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| DC8278 | BVT-14225 Featured | BVT 14225 is a new selective 11b-HSD1 inhibitor, it belongs to a class of arylsulfonamidothiazoles with in vitro and in vivo antidiabetic effects |
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| DC21685 | BVT-948 Featured | BVT-948 (SPS8I-3) is a noncompetitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) with IC50 of 0.09-1.7 uM. Results show that the effect of BVT948 (BVT.948) is to strengthen the insulin signal and has no effects on the duration of th |
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| DC12041 | BW-A 78U Featured | BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. |
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| DC20852 | BX-320 | BX-320 is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 30 nM, >20-fold selectivity over PKA. |
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| DC7675 | BX-471（ZK 811752） Featured | BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1); exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. |
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| DC8808 | BX-513 hydrochloride Featured | BX-513 hydrochloride inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM). |
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| DC8062 | BX517 Featured | BX517 is a novel phosphoinositide-dependent kinase-1 (PDK1) inhibitor. |
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| DC22424 | BX-667 | BX-667 is a potent P2Y12 receptor antagonist that blocks ADP-induced platelet aggregation in human, dog and rat blood (IC50=97, 317 and 3000 nM respectively). |
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| DC7092 | BX795 Featured | BX795 is a potent and selective dual inhibitor of TBK1/PDK1 with IC50s of 2 nM/6 nM respectively; > 50 fold selectivity over PKA, PKC, c-Kit, GSK3β etc. |
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| DC7093 | BX912 Featured | BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1) with IC50 of 12 nM; >10 fold selectivity over PKA, PKC, C-Kit, EGFR etc. |
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| DC11219 | BXI-72 Featured | BXI-72 (NSC334072) is a potent, selective small molecule Bcl-XL inhibitor that targets the BH3 domain of Bcl-XL (Kd=0.9 nM). |
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| DC11058 | BYK191023 | BYK191023 (BYK-191023) is a potent, highly selective inhibitor of inducible nitric-oxide synthase (iNOS) with IC50 of 86 nM, >20-fold selectivity over nNOS and eNOS (IC50=17 and 162 uM). |
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| DC11059 | BYK191023 dihydrochloride | BYK191023 dihydrochloride (BYK-191023) is a potent, highly selective inhibitor of inducible nitric-oxide synthase (iNOS) with IC50 of 86 nM, >20-fold selectivity over nNOS and eNOS (IC50=17 and 162 uM). |
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| DC7094 | Alpelisib(BYL-719) Featured | BYL719 is a potent and selective PI3Kα inhibitor with IC50 of 5 nM, ;liitle or no effect on PI3Kβ/γ/δ. |
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| DC20853 | BZ-194 | BZ-194 is a small molecule inhibitor of NAADP action that inhibit NAADP-mediated Ca2+ signaling in T cells, neither interferes with Ca2+ mobilization by IP3 or cyclic ADP-ribose nor with capacitative Ca2+ entry. |
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| DC20326 | BzDANP | BzDANP is a small molecule modulator of pre-miR-29a maturation by Dicer, effectively stabilizes the C-bulged RNA and suppresses Dicer-mediated processing of pre-miR-29a in a concentration dependent manner.. |
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| DC26049 | Bz-IEGR-pNA (acetate) Featured | Bz-IEGR-pNA is a colorimetric substrate for Factor Xa. |
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| DC11453 | Bz-Nle-Lys-Arg-Arg-AMC Featured | Bz-Nle-Lys-Arg-Arg-AMC is a substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. |
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| DC23462 | C-021 dihydrochloride | C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.. |
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| DC23414 | C-021 | C-021 is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.. |
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| DC10864 | C188-9 Featured | C188-9 is a potent inhibitor of STAT3 that binds to STAT3 with high affinity (KD=4.7±0.4 nM). C188-9 is well tolerated in mice, shows good oral bioavailability, and is concentrated in tumors. |
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| DC20855 | C-215 | C-215 is a novel inhibitor of mycobacterial membrane protein large 3 (MmpL3) with MIC90 of 16 uM against M. tuberculosis.. |
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| DC10937 | C25-140 Featured | C25-140 is a specific, first-in-class small molecule inhibitor of the TRAF6-Ubc13 interaction, binds TRAF6, inhibits TRAF6-Ubc13 interaction and TRAF6 activity. |
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