| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC20021 | Calmidazolium chloride (R 24571) Featured | Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively. Also in anti-cancer re |
|
| DC7095 | W-7 hydrochloride Featured | Calmodulin antagonist. Inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 μM) and myosin light chain kinase (IC50 = 51 μM). |
|
| DC7967 | calpeptin Featured | calpeptin is Ca2+-dependent protease,calpain inhibitor |
|
| DC22045 | CAM4066 | CAM4066 (CAM-4066) is a potent and selective CK2α inhibitor with Kd of 0.32 uM and IC50 of 0.37 uM, shows significantly improved selectivity compared to other CK2α inhibitors. . |
|
| DC22046 | CAM4712 | CAM4712 (CAM-4712) is a potent and selective CK2α inhibitor with IC50 of 7 uM, exhibits cell growth inhibition in HCT116 cell line with IC50 of 10 uM. |
|
| DC8730 | Cambendazol Featured | Cambendazol is an antihelmintic that, at a dose of 50 mg/kg/day in mice, eradicates S. ratti adult worms from intestine and S. stercoralis larva from muscle. |
|
| DC10744 | Cambinol Featured | Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 and 59 μM, respectively. |
|
| DC20330 | CAMKK2 inhibitor 4t | CAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5. |
|
| DC10377 | Campesterol | Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects. |
|
| DC6701 | Camptothecine | Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231. |
|
| DC20859 | CAN-508 Featured | CAN-508 is a potent, selective CDK9 inhibitor with IC50 of 0.35 uM (CDK9/cyclin T1), displays >35 fold selectivity over CDK1/2/4/7 (IC50=13.5-70 uM). |
|
| DC7825 | Canagliflozin hemihydrate | Canagliflozin 0.5 H2O(JNJ 28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1. |
|
| DC3111 | Canagliflozin Featured | Canagliflozin is a highly potent and selective SGLT2 inhibitor for CHO-hSGLT2, CHO-rSGLT2 and CHO-mSGLT2 with IC50 of 4.4 nM, 3.7 nM and 2 nM, respectively. |
|
| DC9185 | Candesartan cilexetil Featured | Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. |
|
| DC9142 | Candesartan | Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM. |
|
| DC8553 | Canertinib Featured | Canertinib (CI-1033) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3. CI-1033 shows excellent potency for irreversible inhibition of erbB2 autophosphorylation in MDA-MB |
|
| DC3138 | Canertinib dihydrochloride Featured | Canertinib dihydrochloride is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. |
|
| DC22425 | Cangrelor sodium Featured | Cangrelor (AR-C69931MX) is a potent, selective P2T/P2Y12 receptor antagonist with IC50 of 0.4 nM against ADP-induced aggregation of human platelets. |
|
| DC7005 | Cangrelor free acid Featured | Cangrelor is a P2Y12 inhibitor, and was approved in June 2015 as an antiplatelet drug for intravenous application. Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggrega |
|
| DC4154 | Capecitabine Featured | Capecitabine is a tumor-selective fluoropyrimidine carbamate which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU. |
|
| DC7615 | Capromorelin Featured | Capromorelin tartrate is a potent ghrelin receptor agonist/growth hormone secretagogue (Ki = 7 nM). |
|
| DC26044 | Caprooyl-Tetrapeptide-3 | Caprooyl tetrapeptide-3 is a derivative of tetrapeptide-3 that is linked to caproic acid. |
|
| DC7952 | Capasazepine Featured | Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, capsaicin; potent TRPV1 receptor antagonist with IC50 of 562 nM. |
|
| DC20331 | Capstafin | Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM. |
|
| DC8975 | Captopril | Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE). |
|
| DC21586 | Capzimin | Capzimin (Rpn11 inhibitor 3027) is a derivative of 8TQ, and potent and specific inhibitor of proteasome isopeptidase Rpn11 with IC50 of 0.34 uM, >7-fold improved potency over 8TQ (quinoline-8-thiol). |
|
| DC9193 | Carbamazepine Featured | Carbamazepine, a sodium channel blocker, is an anticonvulsant drug. |
|
| DCAPI1210 | Carbazochrome sodium sulfonate | Carbazochrome sodium sulfonate |
|
| DC9173 | Carbetapentane citrate | Carbetapentane citrate is a selective inhibitor of the cough, with mild atropine-like effect and local anesthesia effect. |
|
| DC10222 | CarbinoxaMine Maleate | Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties. |
|
