| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23874 | BRD9526 | BRD9526 is a potent, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 60 nM, partially lowers Gli1 expression at concentrations of 10 uM, a useful probe of Shh signaling pathway. . |
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| DC20837 | BRD9757 | BRD9757 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, displays >20-fold selectivity over HDAC1/3 and other HDAC isoforms.. |
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| DC23373 | BRD9-IN-28 | BRD9-IN-28 is a highly potent and selective BRD7/9 bromodomain inhibitor with pIC50 of 6.9, Kd of 68 nM for BRD9. |
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| DC23356 | BRD-IN-17 | BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3. |
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| DC23367 | BRD-IN-26 | BRD-IN-26 is a potent bromodomain inhibitor that binds the fifth bromodomain of PB1 with a KD of 124 nM, SMARCA2B and SMARCA4 with KD values of 262 and 417 nM, respectively. |
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| DC2091 | Brefeldin A | Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells. |
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| DC20981 | Brequinar sodium Featured | Brequinar sodium (DuP-785, Brequinar, NSC 368390) is a potent and selective inhibitor of DHODH with IC50 of 20 nM, triggers differentiation in the ER-HoxA9, U937, and THP1 cells with an ED50 of 1 uM. |
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| DC10605 | Brevianamide F Featured | Brevianamide F , also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. |
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| DC8286 | Brexpiprazole(OPC34712) Featured | Brexpiprazole is a novel D2 dopamine partial agonist. |
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| DC8179 | Briciclib(ON 013105,ON 014185) Featured | Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells. |
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| DC23147 | Brigatinib (AP-26113) Featured | Brigatinib (AP-26113, AP26113) is a potent, selective, second generation ALK inhibitor with IC50 of 0.62 nM, exhibits about fivefold greater potency in vitro compared with crizotinib. |
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| DC4165 | Brinzolamide | Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. |
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| DC2019 | Brivanib (bms-540215) Featured | Brivanib is an ATP-competitive inhibitor against human VEGFR2 and FGFR with IC50 of 25 nM and 148 nM, respectively. |
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| DC9535 | Brivaracetam Featured | Brivaracetam(UCB-34714) is a 4-substituted pyrrolidone butanamide as agent with significant antiepileptic activity; high affinity SV2A ligand and also shows an ability to inhibit Na+ channels. |
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| DC10383 | Brivudine | Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster. |
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| DC21871 | BRK inhibitor P21d | BRK inhibitor P21d is a potent, selective, cell permeable inhibitor of breast tumor kinase (Brk, PTK6) with IC50 of 30 nM, shows no inhibitory activity against Aurora B and Lck (IC50>20 uM). |
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| DC23461 | BRL 37344 sodium | BRL 37344 is a potent and selective β3 adrenoceptor agonist with Ki of 287 nM. |
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| DC7891 | BRL 52537 HYDROCHLORIDE | BRL 52537 is a selective κ/μ opioid receptor agonist. |
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| DC7888 | BRL54443 | BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors. |
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| DC7091 | BRL-15572 dihydrochloride | BRL-15572 2Hcl is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor. |
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| DC20180 | BRL-50481 Featured | BRL-50481 is a novel and selective inhibitor of phosphodiesterase (PDE) 7 with a Ki value, derived from secondary (Dixon) plots, of 180±10 nM, being at least 200-fold selective for hrPDE7A1 over all other PDEs. |
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| DC9124 | Bromhexine HCl | Bromhexine Hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm. |
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| DC22426 | Bromocriptine | Bromocriptine (2-Bromoergocriptine. |
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| DC23899 | Bromocriptine mesylate Featured | Bromocriptine (CB-154) is a dopamine D2 receptor agonist (Ki=3 nM) and and various serotonin receptors, also inhibits the release of glutamate by reversing the glutamate GLT1 transporter. |
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| DC8386 | Bromodeoxyuridine (BrdU) Featured | Bromodeoxyuridine (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA, and used in the detection of proliferating cells. |
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| DC7543 | Bromosporine Featured | Bromosporine is a broad spectrum bromodomain inhibitor. Accelerates FRAP recovery of BRD4 and CREBBP in cells at a concentration of 1 μM. |
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| DC12633 | Bromotriazine | Bromotriazine (BTZ) is a covalent probe against bromodomain containing proteins with selectively targeting non-catalytic, highly conserved amino acid residues.. |
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| DC9141 | Brompheniramine hydrogen maleate | Brompheniramine maleate is a histamine H1 receptors antagonist. |
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| DC23385 | BRPF1B TRIM24-IN-34 | BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively. |
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| DC10913 | Brusatol | Brusatol (NSC 172924, (+)-Brusatol) is a quassinoid extracted from Brucea Esters, can inhibit HIF-1 signaling pathway, also is a potent Nrf2 inhibitor. |
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