| DC20150 |
5-Methoxyflavone |
5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors. |
|
| DC10990 |
5MPN |
5MPN a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3. |
|
| DC23335 |
5-NIdR |
5-NIdR (5-nitro-indolyl-2'-deoxynucleoside) is a non-natural nucleotide produces cytostatic and cytotoxic effects against human leukemia cells by altering cell-cycle progression. |
|
| DC23334 |
5-NITP |
5-NITP (5-nitro-indolyl-2'-deoxyribose triphosphate) is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression.. |
|
| DC9444 |
5-R-Rivaroxaban |
5-R-Rivaroxaban is (R) enantiomer of Rivaroxaban. |
|
| DC7604 |
FAI (5S rRNA modificator)
Featured
|
5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification. |
|
| DC10187 |
666-15
Featured
|
666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM. |
|
| DC20195 |
6-(Dimethylamino)purine；N,N-Dimethyladenine |
6-Dimethylaminopurine is a serine threonine protein kinase inhibitor. It inhibits the germinal vesicle breakdown and the meiotic maturation of oocytes. |
|
| DC23336 |
6-Ethylthioinosine |
6-Ethylthioinosine (6-ETI. |
|
| DC20604 |
6-FABA |
6-FABA (6-Fluoroanthranilic Acid) is a small-molecule inhibitor of MTB tryptophan synthesis that converts Mtb into a tryptophan auxotroph and restores the efficacy of a failed host defense. |
|
| DC9372 |
6-FAM SE
Featured
|
6-FAM SE is another isomer of carboxyfluorescein. |
|
| DC9376 |
6-FITC |
6-Fluorescein isothiocyanate(6-FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. |
|
| DC7736 |
6H05
Featured
|
6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C). |
|
| DC12326 |
6-Hydroxybentazon (6-Hydroxybentazone) |
6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides. |
|
| DC20297 |
6-Hydroxy-DL-DOPA
Featured
|
6-Hydroxy-DL-DOPA is a small-molecule that disrupts with RAD52 oligomerization, inhibits ssDNA binding by RAD52 with IC50 of 1.1 uM and by RAD52 (1 209) with IC50 of 1.6 uM. |
|
| DC8864 |
6-Mercaptopurine (6-MP) Monohydrate |
6-Mercaptopurine Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. |
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|
| DC10854 |
6-MITC
Featured
|
6-MITC is an inhibitor of viability of both PANC-1 and BxPC-3 cells. It also acts as an inhibitor of the expression of CSC signaling molecule SOX2. |
|
| DC12540 |
6-MOMIPP |
6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro. |
|
| DC7925 |
GTPL-5846 (6-OAU)
Featured
|
6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay. |
|
| DC8953 |
6-TG/Thioguanine
Featured
|
6-Thioguanine(6-TG) belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites; it is a purine analogue of the nucleobase guanine. |
|
| DC10215 |
7,8-Dihydroxyflavone |
7,8-Dihydroxyflavone acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF). |
|
| DC7876 |
7ACC2
Featured
|
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells. |
|
| DCAPI1394 |
7-Aminocephalosporanic acid |
7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates. |
|
| DC12463 |
7-BIA |
7-BIA is a small molecule 7-butoxy illudalic acid analog that targets receptor-type protein tyrosine phosphatase D (PTPRD, IC50=1-3 uM) with some specificity. |
|
| DC12215 |
7-Dehydrocholesterol |
7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3. |
|
| DC21513 |
7DG |
7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR. |
|
| DC10855 |
7-Epi 10-Desacetyl Paclitaxel
Featured
|
7-Epi 10-Desacetyl Paclitaxel is a paclitaxel impurity. The compound, originally isolated from Taxus yunnanensis, has shown potential growth inhibitory activities against human cancer cells. |
|
| DC10856 |
7-Epipaclitaxel
Featured
|
7-epi-Taxol is a paclitaxel binds to tubulin, interfering with the normal function of microtubule. |
|
| DC8388 |
8-Bromo-cAMP
Featured
|
8-Bromo-cAMP is a cell perbeable cyclic AMP (cAMP) analog and a PKA activator. |
|
| DC26033 |
8-Hydroxy-efavirenz
Featured
|
8-Hydroxy-efavirenz is the primary metabolite of the antiretroviral drug Efavirenz, stimulates the glycolytic flux in cultured rat astrocytes. |
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