DC23301 |
Bax activator compound 106 |
A specific, small molecule Bax agonist that promotes Bax-dependent but not Bak-dependent apoptosis. |
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DC24150 |
Griseofulvin |
A spirocyclic fungal natural product used in treatment of fungal dermatophytes.. |
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DC22669 |
ONO-1301 |
A stable, orally active, non-prostanoid prostacyclin I2 (PGI2) mimetic and prostacyclin agonist with inhibitory activity against thromboxane A2 synthase. |
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DC26088 |
Stauprimide |
A staurosporine analog that promotes embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME2, which in turn results in down-regulation of MYC transcription. |
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DC22385 |
Adrenosterone |
A steroid hormone with a weak androgenic effect, and an intermediate/prohormone of 11-ketotestosterone.. |
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DC23926 |
Fiacitabine |
A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent. |
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DC24191 |
Cyclophosphamide hydrate |
A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. |
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DC22562 |
OABK hydrochloride |
A synthetic amino acid that fuctions as a small molecule switch for activation of protein function through the site-specific incorporation. |
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DC22546 |
Antibiotic-5d |
A synthetic antimicrobial compound that antibacterial activity in vitro against various Gram-positive and Gram-negative bacteria, fungi and yeast.. |
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DC23906 |
Butenafine hydrochloride |
A synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase. |
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DC20656 |
AM-2201 |
A synthetic cannabinoid that acts as a potent, nonselective full agonist for the cannabinoid receptor with EC50 of 38 and 58 nM for CB1 and CB2, respectively. |
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DC11517 |
Benzodrocortisone |
A synthetic glucocorticoid corticosteroid.. |
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DC11525 |
Mocravimod |
A synthetic immunosuppressant that functions as a S1P1 receptor agonist. |
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DC23705 |
Lenabasum |
A synthetic nonpsychoactive cannabinoid acid with potent analgesic and anti-inflammatory activity in vivo, binds directly and selectively to PPARγ. |
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DC22494 |
ST-2825 |
A synthetic peptido-mimetic compound that inhibits MyD88 dimerization in a TIR-dependent manner. |
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DC22357 |
Benfotiamine |
A synthetic S-acyl derivative of thiamine (vitamin B1) that possesses anti-inflammatory effects. |
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DC22458 |
RX-055 |
A tailored WOBE437-derived diazirine-containing photoaffinity probe that irreversibly blocks membrane transport of both endocannabinoids. |
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DC22474 |
Demeclocycline hydrochloride |
A tetracycline antibiotic that acts by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA which impairs protein synthesis by bacteria. |
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DC7517 |
THIACETAZONE |
A thiosemicarbazone that is used in association with other antimycobacterial agents in the initial and continuation phases of antituberculosis regimens. Thiacetazone containing regimens are less effective than the short-course regimen recommended by the I |
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DC25059 |
BMS-986001 |
A thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM. |
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DC9633 |
Toll-like receptor modulator |
A Toll-like receptor modulator. |
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DC24097 |
Ufenamate |
A topical analgesic that possesses anti-inflammatory effect for treatment of skin diseases, such as acute and chronic eczema, contact dermatitis, diaper dermatitis, miliaria and atopic dermatitis.. |
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DC22457 |
NAPQI |
A toxic byproduct, iminoquinone metabolite of acetaminophen that covalently binds to the active site of MIF. |
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DC24092 |
Posaconazole hydrate |
A triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole.. |
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DC21517 |
Mithramycin A |
A tricyclic pentaglycosidic, antineoplastic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. |
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DC21638 |
SLV peptide |
A tripeptide representing the Fas-C terminus that specifically blocks the interaction of Fap1 with Fas. |
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DC24136 |
Amitifadine hydrochloride |
A triple monoamine reuptake inhibitor that inhibits the reuptake of [3H]serotonin, [3H]norepinephrine, and [3H]dopamine in HEK 293 cells expressing the corresponding human recombinant transporters (IC50 values of 12, 23, and 96 nM, respectively). |
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DC22736 |
Amitifadine |
A triple monoamine reuptake inhibitor, inhibits the reuptake of 5-HT, norepinephrine and dopamine in HEK 293 cells with IC50 of 12, 23 and 96 nM, respectively. |
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DC21185 |
Cucurbitacin I |
A triterpenoid compound that potently and selectively inhibits JAK/STAT3 pathway, suppresses the levels of phosphotyrosine STAT3 in A549 cell with IC50 of 500 nM. |
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DC23062 |
RAMX3 |
A tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM. |
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