| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC22473 | Loxapine | A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.. |
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| DC22477 | Loxapine succinate | A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.. |
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| DC22811 | TX-1123 | A tyrphostin AG17 analog that exihibits potent Src-K inhibitory activity with IC50 of 2.2 uM. |
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| DC24189 | Closantel sodium | A veterinary anthelmintic with known proton ionophore activities. |
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| DC24190 | Closantel | A veterinary anthelmintic with known proton ionophore activities. |
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| DC11578 | VHL Ligand 3 | A VHL ligand for PROTAC.. |
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| DC11581 | VHL Ligand 4 | A VHL ligand for PROTAC.. |
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| DC11580 | VHL-2 | A VHL ligand for PROTAC.. |
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| DC23096 | BCX-4430 | A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator. |
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| DC25095 | BCX4430 freebase | A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator. |
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| DC22579 | Retaspimycin hydrochloride | A water-soluble derivative of 17-AAG and HSP90 inhibitor. |
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| DC22983 | Minnelide | A water-soluble prodrug of triptolide that is highly effective in reducing pancreatic tumor growth and spread, and improving survival. |
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| DC22868 | Propofol | A widely used general anesthetic to induce and maintain anesthesia. |
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| DC23233 | AH 6809 | A xanthone derivative that fuctions as an EP and DP receptor antagonist. |
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| DC22878 | LB-205 | A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo. |
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| DC11491 | A-1048400 | A-1048400(A 1048400) is a novel potent, selective, orally active N-type and T-type calcium channel blocker with IC50 of 1.4 and 1.2 uM, respectively. |
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| DC10920 | A12B4C3 | A12B4C3 (hPNKP inhibitor A12B4C3) is a specific, noncompetitive inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase (hPNKP) with C50 of 60 nM, displays no inhibition of calcineurin and protein phosphatase-1 or APTX. |
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| DC12702 | A1874 | A1874 (A-1874) is a nutlin-based and BRD4-degrading PROTAC with DC50 of 32 nM (induce BRD4 degradation in cells). |
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| DC7044 | A-205804 | A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively. |
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| DC11490 | A-317567 | A-317567 (A317567) is a novel potent acid sensing ion channel (ASIC) blocker with IC50 of 2-30 uM. |
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| DC23659 | A-357300 | A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM, does not inhibit MetAP1 or leucine aminopeptidases at 10 uM. |
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| DC10129 | A395 | A-395 potently inhibited the formation of H3K27me3 (via antagonizing EED in the trimeric PRC2 complex (EZH2:EED:SUZ12)) with IC50 = 34 ± 2 nM (Hill Slope = 0.7) |
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| DC20610 | A-395N | A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM.. |
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| DC20611 | A4250 | A4250 (A-4250, Odevixibat) is a small molecule ileal bile acid transporter (IBAT) inhibitor for the treatment of cholestatic liver diseases including progressive familial intrahepatic cholestasis and NASH.. |
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| DC12317 | A-484954 | A-484954 is a highly selective eukaryotic elongationfactor-2 (eEF2) inhibitor, with an IC50 of 280 nM. |
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| DC20612 | A-68930 hydrochloride | A-68930 is a potent, specific, orally bioavailable agonist of the D1 Dopamine receptor with EC50 of 2.5 nM. |
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| DC7351 | A-740003 | A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). |
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| DC11372 | A-779 | A-779 is a peptide antagonist of the Mas receptor, also known as the angiotensin (1-7) (Ang (1-7)) receptor (IC50 = 0.3 nM in a radioligand binding assay). |
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| DC7785 | A-790742 | A-790742 is a potent human immunodeficiency virus type 1 (HIV-1) protease inhibitor, with 50% effective concentrations ranging from 2 to 7 nM against wild-type HIV-1. |
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| DC20614 | A-832234 | A-832234 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 19 nM.. |
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