Cat. No. | Product name | CAS No. |
DC26089 |
MNS
A potent, selective Src and Syk kinase inhibitor with IC50 of 29.3 uM and 2.5 uM, respectively. |
1485-00-3 |
DC20557 |
STAT3 inhibitor C188
A potent, selective STAT3 inhibitor that blocks STAT3 binding to its phosphopeptide ligand (IC50=20 uM) and inhibits IL-6-mediated phosphorylation of STAT3. |
823828-18-8 |
DC20375 |
Erasin
A potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays. |
|
DC20824 |
BP-5-087
A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation. |
1803281-30-2 |
DC21580 |
RO 5166017
A potent, selective TAAR1 agonist with Ki of 1.9, 2.7, 31 and 24 nM for mouse, rat, cynomolgus monkey and human TAAR1 stably expressed in HEK293 cells. |
1048346-74-2 |
DC20593 |
5Z-7-Oxozeaenol
A potent, selective TAK1 inhibitor with IC50 of 8 nM, displays >33-fold and >62-fold selectivity over MEKK1 and MEKK4 respectively. |
253863-19-3 |
DC22578 |
TPO-Agonist-1
A potent, selective thrombopoietin (TPO) receptor agonist.. |
1033040-23-1 |
DC23548 |
TLR9 inhibitor 18
A potent, selective TLR9 antagonist with IC50 of 13 nM (human TLR9), displays 75-fold selectivity over TLR7 and no activity against TLR8 (IC50>10 uM). |
1351978-48-7 |
DC20878 |
CDK7 and 9 inhibitor 14
A potent, selective transcriptional CDK inhibitor with Ki of 2.3 and 0.38 nM for CDK7 and CDK9, respectively. |
851439-14-0 |
DC22786 |
CB34
A potent, selective translocator protein 18 kDa (TSPO/PBR) agonist with IC50 of 2.59 and 1.03 nM in competing with [3H]-PK11195 for binding to membrane preparations from rat cerebral cortex and ovary, respectively. |
193979-75-8 |
DC21220 |
Larixyl acetate
A potent, selective TRPC6 channel inhibitor with IC50 of 0.1-0.6 uM, 12- and 5-fold selectivity over related TRPC3 and TRPC7. |
4608-49-5 |
DC21820 |
WS-12
A potent, selective TRPM8 agonist with EC50 of 12 uM, a cooling agent. |
68489-09-8 |
DC24043 |
USP8-IN-22e
Featured
A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.28 uM. |
924296-19-5 |
DC24042 |
USP8-IN-22c
A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM. |
924296-17-3 |
DC24041 |
USP8-IN-22d
A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM. |
924296-18-4 |
DC22696 |
BRL 44408
Featured
A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors. |
118343-19-4 |
DC22695 |
BRL 44408 maleate
A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors. |
681806-46-2 |
DC22694 |
ARC 239 dihydrochloride
A potent, selective α2B adrenoceptor antagonist with pKd of 8.8, 200-fold selectivity over α2A, and α2D receptors. |
55974-42-0 |
DC22753 |
NS13001
Featured
A potent, selective, allosteric and orally acitve positive modulator of small-conductance calcium-activated K+ channel KCa2.2 and KCa2.3 with EC50 of 1.6 and 0.14 uM, respectively. |
1063331-94-1 |
DC11745 |
BMS-22
A potent, selective, allosteric CCR2 antagonist with binding IC50 of 5.1 nM. |
445479-97-0 |
DC11744 |
CCR2-RA-[R]
A potent, selective, allosteric CCR2 antagonist with IC50 of 103 nM.. |
512177-83-2 |
DC21316 |
ML400
A potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases. |
1908414-42-5 |