DC6908 |
Bendamustine HCL (SDX-105, Cytostasane)
Featured
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Bendamustine HCL (Ribomustin, Treanda, SDX-105) is a DNA-damaging agent with IC50 of 50 μM. |
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DC12299 |
Benfluralin |
Benfluralin is a kind of herbicide and an agrochemical which can be used as a pre-emergence herbicide used for the control of grass and other weeds in a range of food and non-food crops. |
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DC20185 |
Benzamidine HCl |
Benzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively. |
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DC26053 |
Benzamil (hydrochloride)
Featured
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Benzamil hydrochloride is a specific and potent sodium channel (ENaC) blocker. |
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DC22184 |
Benzarone |
Benzarone (NSC 82134) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=17 uM, EYA3), exhibits selectivity for EYA over PTP1B. |
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DC9885 |
Benzenesulfonamide |
Benzenesulfonamide ia an inhibitor of carbonic anhydrases |
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DC20028 |
Benznidazole (Synonyms: Benznidazol; Ro 07-1051; Ro 71051)
Featured
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Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease. |
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DC10223 |
Benzocaine hydrochloride |
Benzocaine hydrochloride is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. |
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DC12173 |
Benzyl alcohol (Benzenemethanol) |
Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor. |
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DC20216 |
Benzylcetyldimethylammonium chloride hydrate |
Benzylcetyldimethylammonium chloride hydrate is a chemical. |
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DC22482 |
Bephenium hydroxynaphthoate |
Bephenium hydroxynaphthoate is an anthelmintic compound that acts as an activiator of nematode B-type nAChR, is used in the treatment of hookworm infections and ascariasis.. |
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DC22478 |
Bephenium |
Bephenium is an anthelmintic compound that acts as an activiator of nematode B-type nAChR, is used in the treatment of hookworm infections and ascariasis.. |
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DC8898 |
Bepotastine
Featured
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Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. |
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DC21868 |
Berotralstat |
Berotralstat is a potent human plasma kallikrein inhibitor. |
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DC21519 |
Besifovir |
Besifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).. |
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DC11042 |
BET inhibitor CF53 |
BET inhibitor CF53 is a highly potent, orally active inhibitor of bromodomain and extra-terminal (BET) with Ki of <1 nM (BRD4 BD1). |
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DC21382 |
EIDD-1931(NHC)
Featured
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EIDD-1931 (β-d-N4-Hydroxycytidine, NHC) inhibits both murine hepatitis virus (MHV) (EC50 of 0.17 μM) and Middle East respiratory syndrome CoV (MERS-CoV) (EC50 of 0.56 μM) with minimal cytotoxicity. It also inhibits SARS-CoV-2 and multiple 2 endemic, epide |
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DC8830 |
Betahistine
Featured
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Betahistine is a strong affinity histamine H3 receptor antagonist and weak affinity agonist of histamine H1 receptors. |
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DC12320 |
Betanin |
Betanin has potent antioxidant and anti-inflammatory effect, that could inhibit peroxynitrite (ONOO-), with an IC50 of 19.2 μM. Betanin is a red glycoside obtained from beets that can be used as colorant. |
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DC8556 |
BET-BAY 002 |
BET-BAY 002 is a potent BET inhibitor; shows efficacy in a multiple myeloma model. |
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DC11566 |
BETd-260
Featured
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BETd-260 (ZBC260, BETd260) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
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DC11567 |
BETd-260 trifluoroacetate |
BETd-260 trifluoroacetate (ZBC260, BETd 260 TFA) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
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DC12131 |
BF-227(E/Z)
Featured
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BF 227 is a candidate for an amyloid imaging probe for PET, with a Ki of 4.3 nM for Aβ1-42 fibrils. |
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DC20797 |
BF 844 |
BF 844 (BioFocus 844) is a small molecules capable of stabilizing mutant USH3 mutation CLRN1(N48K). |
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DC12136 |
BF-168 |
BF-168, a candidate probe for PET, is found to specifically recognize both neuritic and diffuse plaques, with a Ki of 6.4 nM for Aβ1-42. |
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DC20767 |
BF738735 |
BF738735 is a novel, broad-spectrum inhibitor of enterovirus replication (EC50=4-71 nM) that specifically targets host cell factor PI4KIIIβ with IC50 of 5.7 nM, 300-fold less potent for PI4KIIIα (IC50=1.7 uM). |
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DC10335 |
BGB-3111 |
BGB-3111 is a potent, selective and orally available Bruton's tyrosine kinase (Btk) inhibitor. |
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DC22196 |
BGC20-1531 |
BGC20-1531 (PGN-1531, AP 1531) is a potent, selective prostanoid EP receptor EP antagonist, exhibits high affinity at recombinant human EP4 receptors expressed in cell lines (pKB=7.6) and native EP4 receptors in human cerebral and meningeal artery (pKB=7. |
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DC10059 |
BGG463
Featured
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BGG463 can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively. |
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DC21359 |
BHC
Featured
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BHC, a small-molecule inhibitor of skeletal muscle myosin, effectively suppresses muscle activity by targeting myosin function without altering membrane currents. This compound emerges from a screening process aimed at identifying molecules capable of modulating muscle movement through myosin inhibition. By specifically inhibiting myosin, BHC provides a unique mechanism for controlling muscle contractions while maintaining the integrity of cellular electrical properties. |
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