Cat. No. | Product name | CAS No. |
DC22258 |
ABT-080
ABT-080 is a potent FLAP inhibitor that inhibits ionophore-stimulated LTB(4) formation with with IC50 of 20 nM. |
189498-57-5 |
DC20626 |
ABT-089
ABT-089 (Pozanicline) is a potent, selective α4β2 nAChR agonist with Ki of 16 nM. |
161417-03-4 |
DC21984 |
ABT-100
ABT-100 (ABT100) is a highly selective, potent, orally bioavailable inhibitor of farnesyltransferase (FTase). |
450839-40-4 |
DC20628 |
ABT-102
ABT-102 is a potent, highly selective, orally active TRPV1 antagonist that inhibits agonist-evoked increases in intracellular Ca(2+) levels with IC50 of 5-7 nM. |
808756-71-0 |
DC20629 |
ABT-107
ABT-107 is a potent and selective α7 nAChR agonist with Ki of 0.2-0.6 nM for rat or human cortex α7 nAChRs. |
855291-54-2 |
DC23537 |
ABT-288
ABT-288 is a potent, selective and competitive antagonist of H3 receptor with Ki of 1.9/8.2 nM for human/rat H3 respectively. |
948845-91-8 |
DC4231 |
Linifanib (ABT-869)
Featured
ABT-869 is an ATP-competitive, multi-targeted RTK inhibitor that is completely effective against all members of the vascular endothelial growth factor (VEGF) and platelet derived growth factor (PDGF) receptor families. |
796967-16-3 |
DC20630 |
ABTL0812
ABTL0812 is a novel first-in-class, small molecule that inhibits the Akt/mTORC1 axis and shows antiproliferative effect on tumor cells. |
57818-44-7 |
DC23182 |
ABX464
Featured
ABX464 (ABX-464, ABX 464) is a novel class of anti-HIV small molecule targeting Rev-mediated viral RNA biogenesis, shows dose dependent inhibition of HIV-1 replication in stimulated PBMCs with IC50 of 0.1-0.5 uM. |
1258453-75-6 |
DC11508 |
AC1903
Featured
AC1903 is a specific and selective inhibitor of TRPC5 and has podocyte-protective properties. AC1903 does no effects on TRPC4 or TRPC6 currents and shows no off-target effects in kinase profiling assays. AC1903 suppresses severe proteinuria and prevents podocyte loss in focal segmental glomerulosclerosis (FSGS) rat model. |
831234-13-0 |
DC10293 |
AC260584
AC260584 is an M1 muscarinic receptor allosteric agonist with a pEC50 of 7.6. |
560083-42-3 |
DC11149 |
AC261066
AC261066 (AC-261066, AC261) is a potent, selective, orally available RARβ2 agonist with pEC50 of 8.1, displays selectivity over RARβ1, RARα and RARγ (pEC50=6.4, 6.2 and 6.3). |
870773-76-5 |
DC20631 |
AC-265347
AC-265347 is a calcimimetic acting agent and highly efficacious, orally active allosteric agonist (PAM) of CaSR with IC50 of 10 nM in PI hydrolysis assays. |
1253901-26-6 |
DC20300 |
AC-4-130
AC-4-130 is a novel, potent STAT5 SH2 domain inhibitor, binds to and efficiently blocks STAT5 activation and subsequent transcriptional activity, shows high selectivity for STAT5 over STAT1 and STAT3. |
1834571-82-2 |
DC21863 |
AC5 inhibitor C90
AC5 inhibitor C90 is a novel potent, selective adenylyl cyclase type 5 (AC5) inhibitor with IC50 of 30 nM, >5-fold selectivity over AC2 and AC6 subtypes. |
|
DC12086 |
AC-55649
Featured
AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9. |
59662-49-6 |
DC7700 |
AC710
Featured
AC710, is a potent Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases. |
1351522-04-7 |
DC11359 |
Caspase-3 Substrate
Ac-DNLD-AMC is a fluorogenic caspase-3 substrate. |
958001-92-8 |
DC9900 |
Acetaminophen
Featured
Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively. |
103-90-2 |
DC20115 |
Acetoacetic acid sodium salt
Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes. |
623-58-5 |
DC10248 |
Acetohydroxamic acid
Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease. |
546-88-3 |
DC20151 |
Acetosyringone
Featured
Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself. Acetosyri |
2478-38-8 |