| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC20069 | CHMFL-PI3KD-317 | CHMFL-PI3KD-317 is a highly potent, selective and orally active PI3Kδ inhibitor, with an IC50 of 6 nM, and exhibits over 10-1500 fold selectivity over other class I, II and III PIKK family isoforms, such as PI3Kα (IC50, 62.6 nM), PI3Kβ (IC50, 284 nM), PI3 |
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| DC12199 | Cholestenone | Cholestenone is the intermediate oxidation product of cholesterol. |
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| DC20181 | Choline Fenofibrate;ABT-335 | Choline fenofibrate is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist. |
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| DC22173 | CHR-3996 | CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3. |
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| DC9460 | CHR-6494 Featured | CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. |
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| DC12329 | ChX710 | ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3. |
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| DC10341 | CHZ868 | CHZ868 is a type II JAK2 inhibitor with an IC50 of 0.17 μM in EPOR JAK2 WT Ba/F3 cell. |
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| DC20893 | CI-1044 | CI-1044 is a potent, selective and orally bioavailable PDE4 inhibitor with IC50 of 0.27 uM, displays high selectivity for PDE4 versus PDE1/3/5, and no PDE4 subtype (4A-D) selectivities. |
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| DC21462 | CI-966 | CI-966 (PD 126141) is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively. |
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| DC20894 | CI-966 hydrochloride | CI-966 is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively. |
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| DC21463 | CI-976 Featured | CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM. |
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| DC12412 | cIAP1 E3 ligase inhibitor D19 | cIAP1 E3 ligase inhibitor D19 (cIAP1 inhibitor D19) is a small-molecule inhibitor of E3 ligase activity of cIAP1, inhibits cIAP1 auto-ubiquitination with IC50 of 14.1 uM, shows no effect on autoubiquitination of BRCA1/BARD1. |
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| DC12413 | cIAP1 E3 ligase inhibitor D19-14 | cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14) is an improved analog of D19, demonstrates significantly increased ability to inhibit cIAP1 autoubiquitination and reduce protein levels of c-MYC in vitro. |
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| DC12285 | CID 1375606 Featured | CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. |
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| DC22056 | CID 9998128 | CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils. |
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| DC12243 | CID-1067700 | CID-1067700 is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM. |
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| DC20895 | CID3528206 | CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively. |
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| DC7385 | CID-755673 Featured | CID755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM; exhibits selective PKD1 inhibition when compared with AKT, PLK1, CAK, CAMKIIα, and PKC isoforms. |
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| DC23753 | CID888706 | CID888706 is a small molecule, pan activator of Rho-family GTPases.. |
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| DC20904 | CIDD 0067106 | CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM). |
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| DC11374 | Cilastatin | Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase. |
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| DC9325 | Cilazapril (monohydrate) Featured | Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. |
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| DC20341 | Ciliobrevin D Featured | Ciliobrevin D is a cell-permeable, reversible, specific inhibitor of cytoplasmic dynein, blocks dynein-dependent microtubule gliding and ATPase activity while sparing kinesin dependent cellular trafficking. |
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| DC9582 | Cilomilast | Cilomilast(SB 207499; Ariflo) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. |
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| DC22028 | Ciluprevir | Ciluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively. |
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| DC12134 | Cimiside B | Cimiside B, a glycoside alkaloid, isolated from the rhizome of Cimicifuga dahurica. |
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| DC20093 | Cinchonine ((8R,9S)-Cinchonine; LA40221) Featured | Cinchonine is a natural compound present in Cinchona bark. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. |
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| DC9896 | Cinnarizine Featured | Cinnarizine is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker. |
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| DC21572 | Cipemastat | Cipemastat (Ro 32-3555) is a potent, second-generation, orally active MMP inhibitor, preferentially inhibits collagenases (MMP-1, -8, and -13) and gelatinase B (MMP-9). |
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| DC9603 | Ciprofibrate | Ciprofibrate is a peroxisome proliferator-activated receptor agonist. |
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