| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23856 | CEP-7055 | CEP-7055 is a potent, orally active, pan inhibitor of VEGFR, CEP-7055 is the dimethylglycine ester prodrug of CEP-5214, which inhibits human VEGFR2/KDR kinase, VEGFR1/FLT-1 kinase, and VEGFR3/FLT-4 kinase with IC50 of 18 nM, 12 nM, and 17 nM. |
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| DC10226 | Cefradine | Cephradine is a semi-synthetic cephalosporin antibiotic. |
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| DC7814 | Cerdulatinib(PRT-062070; PRT2070) Featured | Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor. |
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| DC9500 | Cevimeline (hydrochloride hemihydrate) Featured | Cevimeline hydrochloride hemihydrate, a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome. |
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| DC7899 | Cevipabulin(TTI 237) | Cevipabulin, also known as TTI-237, an antimicrotubule agent, is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity. |
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| DC22052 | CFI02 | CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169. |
|
| DC10069 | CFI-400437 Featured | CFI-400437 is potent against PLK4 (IC50 = 0.6 nM) and selective against other members of the PLK family (>10 uM). |
|
| DC23338 | CFI-401980 | CFI-401980 is a potent, selective, novel class TTK (Tyrosine Threonine Kinase) inhibitor with Ki of 0.8 nM, HCT116 GI50 of 13 nM. |
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| DC9340 | CFM-2 | CFM-2 is a selective non-competitive AMPAR antagonist. |
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| DC11133 | CFM-4.16 | CFM-4.16 is a CARP-1 functional mimetic (CFM) compound bind with CARP-1, stimulates CARP-1 expression and apoptosis. |
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| DC22809 | c-FMS-IN-8 Featured | c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.. |
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| DC9849 | CGP37849 | CGP37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). Anticonvulsive following oral administration in vivo. |
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| DC23919 | CGP-42112 Featured | CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM. |
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| DC23830 | CGP-53353 | CGP-53353 (DAPH-7) is a selective inhibitor of PKCβII with IC50 of 0.41 uM, shows weak activity on PKCβI with IC50 of 3.8 uM. |
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| DC20887 | CGP-74514A hydrochloride | CGP-74514A hydrochloride is a potent CDK1 inhibitor with IC50 of 25 nM. |
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| DC24112 | CGS 21680 | CGS 21680 is a specific adenosine A2A subtype receptor agonist with Ki of 27 nM. |
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| DC21331 | CGS 27023A | CGS 27023A (MMI 270) is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9. |
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| DC10974 | Ch-319 | Ch-319 (Ch319) is a triphenyltin (IV) carboxylate derivative that modulates AKT/FOXO3a signaling and inhibits progression of prostate cancer. |
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| DC20337 | Chaetocin | Chaetocin is a potent, specific, SAM-competitive inhibitor of histone H3K9 methyltransferase (HMT) SU(VAR)3-9 with IC50 of 0.6 uM, no actiivty against H4 Lys20-specific HMT PRSET7 and SET7/9. |
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| DC5135 | Chaetominine | Chaetominine , an alkaloidal metabolite with a new framework, was characterized from the solid-substrate culture of Chaetomium sp. |
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| DC12545 | CHDI-390576 Featured | CHDI-390576 (CHDI390576) is a potent, cell permeable and CNS penetrant class IIa HDAC inhibitor with IC50 of 54/60/31/50 nM for HDAC4/5/7/9, respectively. |
|
| DC20100 | Chelidonic acid Featured | Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blo |
|
| DC12205 | CHEMBL333994 (FK-480) | CHEMBL333994 is a potent and orally effective Cholecystokinin A (CCK-A) antagonist, with an IC50 of 0.67 nM. |
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| DC20338 | Chemocoxib A | Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively. |
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| DC21405 | Chetomin Featured | Chetomin (NSC 289491) is a natural product isolated from Chaetomium species which shows antibacterial and antifungal properties, disrupts the interaction of HIF-1α/p300 at low nanomolar concentrations, strongly increases retinal pigment epithelial cells d |
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| DC12515 | Chiglitazar | Chiglitazar (CS-038, CS038) is a potent, dual PPARα/γ dual agonist with EC50 of 1.2, 0.08, 1.7 uM for PPARα, PPARγ and PPARδ, respectively. |
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| DC12323 | CHK1-IN-2 | CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM |
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| DC12124 | Chlorantraniliprole Featured | Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myobla |
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| DC20623 | CHMFL-ABL-053 | CHMFL-ABL-053 is a potent, selective and orally available Bcr-Abl/Src/p38 kinase inhibitor with IC50 of 70/62/90 nM. |
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| DC20339 | CHMFL-KIT-031 | CHMFL-KIT-031 is a highly selective KIT kinase primary V559D mutant inhibitor with IC50/Kd of 28/266 nM, 10-20 fold selectivity over KIT wt. |
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