| DC9835 |
Cytochalasin H
Featured
|
Cytochalasin H is a potent inhibitor of actin incorporation into filaments,a cell-permeable fungal toxin used in actin polymerization studies and cytological research. |
|
| DC7734 |
CZC24832
Featured
|
CZC24832 is the first selective PI3Kγinhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ. |
|
| DC9886 |
D-(+)-Cellobiose |
D-(+)-Cellobiose is a substrate of β-glucosidase. |
|
| DC12252 |
D,L-Buthionine-(S,R)-sulfoximine
Featured
|
D,L-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis. |
|
| DC12582 |
D13-9001 |
D13-9001 (D 13-9001) is a small molecule, MexAB-OprM specific efflux pump inhibitor with good potency in vitro (MPC 2 ug/mL) and displays excellent activity in vivo in a rat pneumonia model of P. aeruginosa.. |
|
| DC25001 |
D-156844 |
D156844 is a potent SMN2 inducer and DcpS inhibitor. |
|
| DC12610 |
D159153 |
D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively.. |
|
| DC20219 |
D159687
Featured
|
D159687 is a selective negative allosteric modulator (NAM) of PDE4D. |
|
| DC9850 |
D-3263 HCl
Featured
|
D3263 is a novel, orally bioavailable small molecule Trp-p8 agonist. |
|
| DC20053 |
D5D-IN-326 |
D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and d |
|
| DC7393 |
D-64131
Featured
|
D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin. |
|
| DC20353 |
Dafadine A
Featured
|
Dafadine A is the first reported small-molecule DAF-9 cytochrome P450 inhibitor that robustly induces dauer formation in in the nematode Caenorhabditis elegans. |
|
| DC21469 |
Dagrocorat |
Dagrocorat (PF 00251802) is a potent, selective high-affinity dissociated agonist of the glucocorticoid receptor.. |
|
| DC23077 |
Daidzin
Featured
|
Daidzin is a potent, selective aldehyde dehydrogenase 2 (ALDH2,IC50 = 80 nM) inhibitor, which has antiallergic anti-oxidant, anti-carcinogenic, antithrombotic,and anti-atherosclerotic activities |
|
| DC3163 |
Dalcetrapib (JTT-705)
Featured
|
Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM. |
|
| DC22810 |
Damnacanthal |
Damnacanthal is a highly potent, selective inhibitor of p56 lck tyrosine kinase with IC50 of 17 nM for inhibition of p56lck autophosphorylation. |
|
| DC21881 |
Danicamtiv (MYK-491)
Featured
|
Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency. |
|
| DCAPI1028 |
Danofloxacin Mesylate |
Danofloxacin Mesylate |
|
| DC12338 |
Dansylamide |
Dansyl amide is a fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group. |
|
| DC20170 |
Dapagliflozin propanediol monohydrate
Featured
|
Dapagliflozin propanediol belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors. |
|
| DC20941 |
DAPH-1
Featured
|
DAPH-1 (CGP 52411) is a small molecule that directly inhibits prion protein Sup35 prionogenesis with IC50 of 0.58 uM, inhibits and reverses the formation of Aβ42 fibers and reduces their toxicity to neurons in culture. |
|
| DC20354 |
DAPH-12 |
DAPH-12 is a small molecule that directly inhibits and reverses prion protein Sup35 prionogenesis (IC50=0.18 uM). |
|
| DC7395 |
Dapivirine
Featured
|
Dapivirine(TMC 120, TMC 120 R147681) is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. |
|
| DC10259 |
Dapson |
Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. |
|
| DC1050 |
Daptomycin
Featured
|
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms. |
|
| DCAPI1440 |
Darifenacin HBr |
Darifenacin Hydrobromide is an antagonist of the M3 musarinnic acetylcholine receptor. |
|
| DC3152 |
Darifenacin |
Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9. |
|
| DC3140 |
Dasatinib monohydrate
Featured
|
Dasatinib is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. |
|
| DC21381 |
Dasolampanel |
Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.. |
|
| DC8162 |
Dasotraline(SEP-225289) free base
Featured
|
Dasotraline(SEP-225289) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. |
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